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HA-HIF1alpha P402A/P564A-pBabe-puro Citations (18)

Plasmid Article: The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.
Yan Q, Bartz S, Mao M, Li L, Kaelin WG Mol Cell Biol. 2007 Mar . 27(6):2092-102.
PubMed Journal

Articles Citing HA-HIF1alpha P402A/P564A-pBabe-puro

Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90. Trisciuoglio D, Gabellini C, Desideri M, Ziparo E, Zupi G, Del Bufalo D. PLoS One. 2010 Jul 27;5(7):e11772. doi: 10.1371/journal.pone.0011772. PubMed
Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. Tamama K, Kawasaki H, Kerpedjieva SS, Guan J, Ganju RK, Sen CK. J Cell Biochem. 2011 Mar;112(3):804-17. doi: 10.1002/jcb.22961. PubMed
Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct. Zhou W, Dosey TL, Biechele T, Moon RT, Horwitz MS, Ruohola-Baker H. PLoS One. 2011;6(11):e27460. doi: 10.1371/journal.pone.0027460. Epub 2011 Nov 23. PubMed

Associated Plasmids

HIF1alpha induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. Zhou W, Choi M, Margineantu D, Margaretha L, Hesson J, Cavanaugh C, Blau CA, Horwitz MS, Hockenbery D, Ware C, Ruohola-Baker H. EMBO J. 2012 May 2;31(9):2103-16. doi: 10.1038/emboj.2012.71. Epub 2012 Mar 23. PubMed
Defining Akt actions in muscle differentiation. Gardner S, Anguiano M, Rotwein P. Am J Physiol Cell Physiol. 2012 Dec 15;303(12):C1292-300. doi: 10.1152/ajpcell.00259.2012. Epub 2012 Oct 17. PubMed
Estrogen receptor beta sustains epithelial differentiation by regulating prolyl hydroxylase 2 transcription. Mak P, Chang C, Pursell B, Mercurio AM. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4708-13. doi: 10.1073/pnas.1221654110. Epub 2013 Mar 4. PubMed
Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells. Onnis B, Fer N, Rapisarda A, Perez VS, Melillo G. J Clin Invest. 2013 Apr;123(4):1615-29. doi: 10.1172/JCI59623. Epub 2013 Mar 15. PubMed
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Cell. 2013 Dec 19;155(7):1624-38. doi: 10.1016/j.cell.2013.11.037. PubMed
Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency. Mathieu J, Zhou W, Xing Y, Sperber H, Ferreccio A, Agoston Z, Kuppusamy KT, Moon RT, Ruohola-Baker H. Cell Stem Cell. 2014 May 1;14(5):592-605. doi: 10.1016/j.stem.2014.02.012. Epub 2014 Mar 20. PubMed
Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth. Vindrieux D, Devailly G, Augert A, Le Calve B, Ferrand M, Pigny P, Payen L, Lambeau G, Perrais M, Aubert S, Simonnet H, Dante R, Bernard D. Oncotarget. 2014 Feb 28;5(4):1004-13. PubMed
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16. PubMed
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1alpha. Tosatto A, Sommaggio R, Kummerow C, Bentham RB, Blacker TS, Berecz T, Duchen MR, Rosato A, Bogeski I, Szabadkai G, Rizzuto R, Mammucari C. EMBO Mol Med. 2016 May 2;8(5):569-85. doi: 10.15252/emmm.201606255. PubMed
Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression. Voss DM, Spina R, Carter DL, Lim KS, Jeffery CJ, Bar EE. Sci Rep. 2017 Jun 27;7(1):4292. doi: 10.1038/s41598-017-04612-w. PubMed
Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis. Kuang Y, Han X, Xu M, Yang Q. Cancer Med. 2018 Apr;7(4):1416-1429. doi: 10.1002/cam4.1410. Epub 2018 Mar 13. PubMed
Sox17 is required for endothelial regeneration following inflammation-induced vascular injury. Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth PT, Benevolenskaya EV, Rehman J, Malik AB. Nat Commun. 2019 May 9;10(1):2126. doi: 10.1038/s41467-019-10134-y. PubMed
Hydrogen sulfide modulates epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via HIF-1alpha activation. Wang M, Yan J, Cao X, Hua P, Li Z. Biochem Pharmacol. 2020 Feb;172:113775. doi: 10.1016/j.bcp.2019.113775. Epub 2019 Dec 20. PubMed
MicroRNA-574-5p in gastric cancer cells promotes angiogenesis by targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3). Zhang S, Zhang R, Xu R, Shang J, He H, Yang Q. Gene. 2020 Apr 5;733:144383. doi: 10.1016/j.gene.2020.144383. Epub 2020 Jan 20. PubMed
Metformin suppresses HIF-1alpha expression in cancer-associated fibroblasts to prevent tumor-stromal cross talk in breast cancer. Shao S, Zhao L, An G, Zhang L, Jing X, Luo M, Li W, Meng D, Ning Q, Zhao X, Lei J. FASEB J. 2020 Jun 27. doi: 10.1096/fj.202000951RR. PubMed

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