Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

HA-HIF2alpha-P405A/P531A-pBabe-puro Citations (7)

Originally described in: The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.
Yan Q, Bartz S, Mao M, Li L, Kaelin WG Mol Cell Biol. 2007 Mar . 27(6):2092-102.
PubMed Journal

Articles Citing HA-HIF2alpha-P405A/P531A-pBabe-puro

Articles
Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. Tamama K, Kawasaki H, Kerpedjieva SS, Guan J, Ganju RK, Sen CK. J Cell Biochem. 2011 Mar;112(3):804-17. doi: 10.1002/jcb.22961. PubMed
Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct. Zhou W, Dosey TL, Biechele T, Moon RT, Horwitz MS, Ruohola-Baker H. PLoS One. 2011;6(11):e27460. doi: 10.1371/journal.pone.0027460. Epub 2011 Nov 23. PubMed

Associated Plasmids

Identification of CDCP1 as a hypoxia-inducible factor 2alpha (HIF-2alpha) target gene that is associated with survival in clear cell renal cell carcinoma patients. Emerling BM, Benes CH, Poulogiannis G, Bell EL, Courtney K, Liu H, Choo-Wing R, Bellinger G, Tsukazawa KS, Brown V, Signoretti S, Soltoff SP, Cantley LC. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3483-8. doi: 10.1073/pnas.1222435110. Epub 2013 Feb 1. PubMed
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Cell. 2013 Dec 19;155(7):1624-38. doi: 10.1016/j.cell.2013.11.037. PubMed
Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency. Mathieu J, Zhou W, Xing Y, Sperber H, Ferreccio A, Agoston Z, Kuppusamy KT, Moon RT, Ruohola-Baker H. Cell Stem Cell. 2014 May 1;14(5):592-605. doi: 10.1016/j.stem.2014.02.012. Epub 2014 Mar 20. PubMed
Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth. Vindrieux D, Devailly G, Augert A, Le Calve B, Ferrand M, Pigny P, Payen L, Lambeau G, Perrais M, Aubert S, Simonnet H, Dante R, Bernard D. Oncotarget. 2014 Feb 28;5(4):1004-13. PubMed
Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression. Voss DM, Spina R, Carter DL, Lim KS, Jeffery CJ, Bar EE. Sci Rep. 2017 Jun 27;7(1):4292. doi: 10.1038/s41598-017-04612-w. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.