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pRK5-HA GST RagB wt Citations (14)

Originally described in: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501. PubMed Journal

Articles Citing pRK5-HA GST RagB wt

Articles
Glutaminolysis activates Rag-mTORC1 signaling. Duran RV, Oppliger W, Robitaille AM, Heiserich L, Skendaj R, Gottlieb E, Hall MN. Mol Cell. 2012 Aug 10;47(3):349-58. doi: 10.1016/j.molcel.2012.05.043. Epub 2012 Jun 29. PubMed
Characteristics and requirements of basal autophagy in HEK 293 cells. Musiwaro P, Smith M, Manifava M, Walker SA, Ktistakis NT. Autophagy. 2013 Sep;9(9):1407-17. doi: 10.4161/auto.25455. Epub 2013 Jun 20. PubMed
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Rebsamen M, Pochini L, Stasyk T, de Araujo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G. Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7. PubMed
Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. Sci Rep. 2015 Mar 30;5:9502. doi: 10.1038/srep09502. PubMed
PRL-3 activates mTORC1 in Cancer Progression. Ye Z, Al-Aidaroos AQ, Park JE, Yuen HF, Zhang SD, Gupta A, Lin Y, Shen HM, Zeng Q. Sci Rep. 2015 Nov 24;5:17046. doi: 10.1038/srep17046. PubMed
Recurrent mutations in the MTOR regulator RRAGC in follicular lymphoma. Ying ZX, Jin M, Peterson LF, Bernard D, Saiya-Cork K, Yildiz M, Wang S, Kaminski M, Chang A, Klionsky DJ, Malek S. Clin Cancer Res. 2016 Jun 7. pii: clincanres.0609.2016. PubMed
Dynamics of mTORC1 activation in response to amino acids. Manifava M, Smith M, Rotondo S, Walker S, Niewczas I, Zoncu R, Clark J, Ktistakis NT. Elife. 2016 Oct 11;5. pii: e19960. doi: 10.7554/eLife.19960. PubMed
TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer. Cooper JM, Ou YH, McMillan EA, Vaden RM, Zaman A, Bodemann BO, Makkar G, Posner BA, White MA. Cancer Res. 2017 Sep 15;77(18):5077-5094. doi: 10.1158/0008-5472.CAN-17-0829. Epub 2017 Jul 17. PubMed
Galectins Control mTOR in Response to Endomembrane Damage. Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V. Mol Cell. 2018 Apr 5;70(1):120-135.e8. doi: 10.1016/j.molcel.2018.03.009. PubMed

Associated Plasmids
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Son SM, Park SJ, Lee H, Siddiqi F, Lee JE, Menzies FM, Rubinsztein DC. Cell Metab. 2019 Jan 8;29(1):192-201.e7. doi: 10.1016/j.cmet.2018.08.013. Epub 2018 Sep 6. PubMed

Associated Plasmids
Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Pal R, Palmieri M, Chaudhury A, Klisch TJ, di Ronza A, Neilson JR, Rodney GG, Sardiello M. Nat Commun. 2018 Oct 19;9(1):4351. doi: 10.1038/s41467-018-06844-4. PubMed
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Odle RI, Walker SA, Oxley D, Kidger AM, Balmanno K, Gilley R, Okkenhaug H, Florey O, Ktistakis NT, Cook SJ. Mol Cell. 2020 Jan 16;77(2):228-240.e7. doi: 10.1016/j.molcel.2019.10.016. Epub 2019 Nov 13. PubMed
Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Bodineau C, Tome M, Courtois S, Costa ASH, Sciacovelli M, Rousseau B, Richard E, Vacher P, Parejo-Perez C, Bessede E, Varon C, Soubeyran P, Frezza C, Murdoch PDS, Villar VH, Duran RV. Nat Commun. 2021 Aug 10;12(1):4814. doi: 10.1038/s41467-021-25079-4. PubMed
Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling. Mohanasundaram P, Coelho-Rato LS, Modi MK, Urbanska M, Lautenschlager F, Cheng F, Eriksson JE. PLoS Biol. 2022 Sep 13;20(9):e3001737. doi: 10.1371/journal.pbio.3001737. eCollection 2022 Sep. PubMed

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