Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM
Science. 2008 Jun 13. 320(5882):1496-501. PubMed Journal
Plasmids from Article
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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Cell. 2010 Apr 16. 141(2):290-303.
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding. Wang L, Harris TE, Roth RA, Lawrence JC. J Biol Chem. 2007 Jul 6. 282(27):20036-44.
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Mol Cell. 2007 Mar 23. 25(6):903-15.
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. Curr Biol. 2003 Aug 5. 13(15):1259-68.