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pRK5-HA GST RagC 120L Citations (10)

Originally described in: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501. PubMed Journal

Articles Citing pRK5-HA GST RagC 120L

Articles
A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. Cully M, Genevet A, Warne P, Treins C, Liu T, Bastien J, Baum B, Tapon N, Leevers SJ, Downward J. Mol Cell Biol. 2010 Jan;30(2):481-95. doi: 10.1128/MCB.00688-09. Epub 2009 Nov 16. PubMed
Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine. Hong-Brown LQ, Brown CR, Kazi AA, Navaratnarajah M, Lang CH. Am J Physiol Cell Physiol. 2012 May 15;302(10):C1557-65. doi: 10.1152/ajpcell.00407.2011. Epub 2012 Mar 21. PubMed
Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes. Martina JA, Puertollano R. J Cell Biol. 2013 Feb 18;200(4):475-91. doi: 10.1083/jcb.201209135. Epub 2013 Feb 11. PubMed
Preliminary functional assessment and classification of DEPDC5 variants associated with focal epilepsy. van Kranenburg M, Hoogeveen-Westerveld M, Nellist M. Hum Mutat. 2015 Feb;36(2):200-9. doi: 10.1002/humu.22723. Epub 2014 Nov 27. PubMed
The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice. Khayati K, Antikainen H, Bonder EM, Weber GF, Kruger WD, Jakubowski H, Dobrowolski R. FASEB J. 2017 Feb;31(2):598-609. doi: 10.1096/fj.201600915R. Epub 2016 Oct 25. PubMed
Galectins Control mTOR in Response to Endomembrane Damage. Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V. Mol Cell. 2018 Apr 5;70(1):120-135.e8. doi: 10.1016/j.molcel.2018.03.009. PubMed

Associated Plasmids
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis. Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn JHM, Zhen X, Wang G, Ying Z. Aging Cell. 2020 Apr;19(4):e13126. doi: 10.1111/acel.13126. Epub 2020 Feb 25. PubMed
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex. Hirst J, Hesketh GG, Gingras AC, Robinson MS. J Cell Biol. 2021 Feb 1;220(2). pii: 211690. doi: 10.1083/jcb.202002075. PubMed
Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies. Akwa Y, Di Malta C, Zallo F, Gondard E, Lunati A, Diaz-de-Grenu LZ, Zampelli A, Boiret A, Santamaria S, Martinez-Preciado M, Cortese K, Kordower JH, Matute C, Lozano AM, Capetillo-Zarate E, Vaccari T, Settembre C, Baulieu EE, Tampellini D. Autophagy. 2023 Feb;19(2):660-677. doi: 10.1080/15548627.2022.2095791. Epub 2022 Jul 22. PubMed
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Malik N, Ferreira BI, Hollstein PE, Curtis SD, Trefts E, Weiser Novak S, Yu J, Gilson R, Hellberg K, Fang L, Sheridan A, Hah N, Shadel GS, Manor U, Shaw RJ. Science. 2023 Apr 21;380(6642):eabj5559. doi: 10.1126/science.abj5559. Epub 2023 Apr 21. PubMed

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