Flag pLJM1 RagD wt Citations (4)
Originally described in: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501. PubMed Journal
Articles Citing Flag pLJM1 RagD wt
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| Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes. Ogmundsdottir MH, Heublein S, Kazi S, Reynolds B, Visvalingam SM, Shaw MK, Goberdhan DC. PLoS One. 2012;7(5):e36616. doi: 10.1371/journal.pone.0036616. Epub 2012 May 4. PubMed |
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A.
Son SM, Park SJ, Lee H, Siddiqi F, Lee JE, Menzies FM, Rubinsztein DC.
Cell Metab. 2019 Jan 8;29(1):192-201.e7. doi: 10.1016/j.cmet.2018.08.013. Epub 2018 Sep 6.
PubMed
Associated Plasmids |
| PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation. Amick J, Tharkeshwar AK, Talaia G, Ferguson SM. J Cell Biol. 2020 Jan 6;219(1):e201906076. doi: 10.1083/jcb.201906076. PubMed |
| Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kalpha Inhibitors. Cai Y, Xu G, Wu F, Michelini F, Chan C, Qu X, Selenica P, Ladewig E, Castel P, Cheng Y, Zhao A, Jhaveri K, Toska E, Jimenez M, Jacquet A, Tran-Dien A, Andre F, Chandarlapaty S, Reis-Filho JS, Razavi P, Scaltriti M. Cancer Res. 2021 May 1;81(9):2470-2480. doi: 10.1158/0008-5472.CAN-20-3232. Epub 2021 Mar 8. PubMed |
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