3XFlagNICD1 Citations (29)
Originally described in: Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.Ong CT, Cheng HT, Chang LW, Ohtsuka T, Kageyama R, Stormo GD, Kopan R J Biol Chem. 2006 Feb 24. 281(8):5106-19. PubMed Journal
Articles Citing 3XFlagNICD1
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| APP intracellular domain-WAVE1 pathway reduces amyloid-beta production. Ceglia I, Reitz C, Gresack J, Ahn JH, Bustos V, Bleck M, Zhang X, Martin G, Simon SM, Nairn AC, Greengard P, Kim Y. Nat Med. 2015 Sep;21(9):1054-9. doi: 10.1038/nm.3924. Epub 2015 Aug 17. PubMed |
| miRNA-34a reduces neointima formation through inhibiting smooth muscle cell proliferation and migration. Chen Q, Yang F, Guo M, Wen G, Zhang C, Luong le A, Zhu J, Xiao Q, Zhang L. J Mol Cell Cardiol. 2015 Dec;89(Pt A):75-86. doi: 10.1016/j.yjmcc.2015.10.017. Epub 2015 Oct 19. PubMed |
| Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Zhang S, Schneider LS, Vick B, Grunert M, Jeremias I, Menche D, Muller R, Vollmar AM, Liebl J. Oncotarget. 2015 Dec 22;6(41):43508-28. doi: 10.18632/oncotarget.6180. PubMed |
A genetic cell context-dependent role for ZEB1 in lung cancer.
Zhang T, Guo L, Creighton CJ, Lu Q, Gibbons DL, Yi ES, Deng B, Molina JR, Sun Z, Yang P, Yang Y.
Nat Commun. 2016 Jul 26;7:12231. doi: 10.1038/ncomms12231.
PubMed
Associated Plasmids |
| BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development. Zhou W, He Q, Zhang C, He X, Cui Z, Liu F, Li W. Elife. 2016 Oct 10;5. pii: e18108. doi: 10.7554/eLife.18108. PubMed |
| Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6. Mouillesseaux KP, Wiley DS, Saunders LM, Wylie LA, Kushner EJ, Chong DC, Citrin KM, Barber AT, Park Y, Kim JD, Samsa LA, Kim J, Liu J, Jin SW, Bautch VL. Nat Commun. 2016 Nov 11;7:13247. doi: 10.1038/ncomms13247. PubMed |
| Hippo signaling interactions with Wnt/beta-catenin and Notch signaling repress liver tumorigenesis. Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y. J Clin Invest. 2017 Jan 3;127(1):137-152. doi: 10.1172/JCI88486. Epub 2016 Nov 21. PubMed |
| PKCtheta links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton. Britton GJ, Ambler R, Clark DJ, Hill EV, Tunbridge HM, McNally KE, Burton BR, Butterweck P, Sabatos-Peyton C, Hampton-O'Neil LA, Verkade P, Wulfing ChC, Wraith DC. Elife. 2017 Jan 31;6. doi: 10.7554/eLife.20003. PubMed |
| Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia. Liu L, Xiao W. BMC Ophthalmol. 2017 Aug 1;17(1):135. doi: 10.1186/s12886-017-0532-1. PubMed |
| Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT-1 by a Notch-dependent mechanism. Lee ML, Martinez-Lozada Z, Krizman EN, Robinson MB. J Neurochem. 2017 Dec;143(5):489-506. doi: 10.1111/jnc.14135. Epub 2017 Sep 5. PubMed |
| Oncogenic Determination of a Broad Spectrum of Phenotypes of Hepatocyte-Derived Mouse Liver Tumors. Yamamoto M, Xin B, Watanabe K, Ooshio T, Fujii K, Chen X, Okada Y, Abe H, Taguchi Y, Miyokawa N, Furukawa H, Nishikawa Y. Am J Pathol. 2017 Dec;187(12):2711-2725. doi: 10.1016/j.ajpath.2017.07.022. Epub 2017 Sep 28. PubMed |
| Area-Specific Regulation of Quiescent Neural Stem Cells by Notch3 in the Adult Mouse Subependymal Zone. Kawai H, Kawaguchi D, Kuebrich BD, Kitamoto T, Yamaguchi M, Gotoh Y, Furutachi S. J Neurosci. 2017 Dec 6;37(49):11867-11880. doi: 10.1523/JNEUROSCI.0001-17.2017. Epub 2017 Nov 3. PubMed |
Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.
Suzuki IK, Gacquer D, Van Heurck R, Kumar D, Wojno M, Bilheu A, Herpoel A, Lambert N, Cheron J, Polleux F, Detours V, Vanderhaeghen P.
Cell. 2018 May 31;173(6):1370-1384.e16. doi: 10.1016/j.cell.2018.03.067. Epub 2018 May 31.
PubMed
Associated Plasmids |
| The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking. Li B, Wong C, Gao SM, Zhang R, Sun R, Li Y, Song Y. Elife. 2018 Sep 4;7. pii: 38181. doi: 10.7554/eLife.38181. PubMed |
| Cerium Oxide Nanoparticles Sensitize Pancreatic Cancer to Radiation Therapy through Oxidative Activation of the JNK Apoptotic Pathway. Wason MS, Lu H, Yu L, Lahiri SK, Mukherjee D, Shen C, Das S, Seal S, Zhao J. Cancers (Basel). 2018 Sep 1;10(9). pii: cancers10090303. doi: 10.3390/cancers10090303. PubMed |
| Src kinase phosphorylates Notch1 to inhibit MAML binding. LaFoya B, Munroe JA, Pu X, Albig AR. Sci Rep. 2018 Oct 19;8(1):15515. doi: 10.1038/s41598-018-33920-y. PubMed |
| A comparison of resveratrol and other polyphenolic compounds on Notch activation and endothelial cell activity. LaFoya B, Munroe JA, Albig AR. PLoS One. 2019 Jan 17;14(1):e0210607. doi: 10.1371/journal.pone.0210607. eCollection 2019. PubMed |
| Icariin promotes osteogenic differentiation by suppressing Notch signaling. Xu Y, Li L, Tang Y, Yang J, Jin Y, Ma C. Eur J Pharmacol. 2019 Dec 15;865:172794. doi: 10.1016/j.ejphar.2019.172794. Epub 2019 Nov 13. PubMed |
| NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis. Salameti V, Bhosale PG, Ames-Draycott A, Sipila K, Watt FM. Oncotarget. 2019 Nov 26;10(63):6791-6804. doi: 10.18632/oncotarget.27306. eCollection 2019 Nov 26. PubMed |
| Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Rodrigues DC, Harvey EM, Suraj R, Erickson SL, Mohammad L, Ren M, Liu H, He G, Kaplan DR, Ellis J, Yang G. Nat Commun. 2020 Apr 24;11(1):2018. doi: 10.1038/s41467-020-15941-2. PubMed |
| BRAF(V600E) Overrides NOTCH Signaling in Thyroid Cancer. Traversi F, Stooss A, Dettmer MS, Charles RP. Thyroid. 2021 May;31(5):787-799. doi: 10.1089/thy.2019.0595. Epub 2020 Nov 12. PubMed |
| Notch family members follow stringent requirements for intracellular domain dimerization at sequence-paired sites. Crow JJ, Albig AR. PLoS One. 2020 Nov 24;15(11):e0234101. doi: 10.1371/journal.pone.0234101. eCollection 2020. PubMed |
| Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells. Shi M, Ren S, Chen H, Li J, Huang C, Li Y, Han Y, Li Y, Sun Z, Chen X, Xiong Z. J Pathol. 2021 Apr;253(4):384-395. doi: 10.1002/path.5602. Epub 2021 Jan 18. PubMed |
| Class II phosphatidylinositol 3-kinase-C2alpha is essential for Notch signaling by regulating the endocytosis of gamma-secretase in endothelial cells. Shimizu S, Yoshioka K, Aki S, Takuwa Y. Sci Rep. 2021 Mar 4;11(1):5199. doi: 10.1038/s41598-021-84548-4. PubMed |
| Critical role of the BAF chromatin remodeling complex during murine neural crest development. Bi-Lin KW, Seshachalam PV, Tuoc T, Stoykova A, Ghosh S, Singh MK. PLoS Genet. 2021 Mar 22;17(3):e1009446. doi: 10.1371/journal.pgen.1009446. eCollection 2021 Mar. PubMed |
| Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte beta-selection. Liu X, Yu J, Xu L, Umphred-Wilson K, Peng F, Ding Y, Barton BM, Lv X, Zhao MY, Sun S, Hong Y, Qi L, Adoro S, Chen X. Elife. 2021 Jul 9;10. pii: 69975. doi: 10.7554/eLife.69975. PubMed |
| Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations. Greenough MA, Lane DJR, Balez R, Anastacio HTD, Zeng Z, Ganio K, McDevitt CA, Acevedo K, Belaidi AA, Koistinaho J, Ooi L, Ayton S, Bush AI. Cell Death Differ. 2022 Apr 21. pii: 10.1038/s41418-022-01003-1. doi: 10.1038/s41418-022-01003-1. PubMed |
| Iron-responsive element of Divalent metal transporter 1 (Dmt1) controls Notch-mediated cell fates. Hounjet J, Groot AJ, Piepers JP, Kranenburg O, Zwijnenburg DA, Rapino FA, Koster JB, Kampen KR, Vooijs MA. FEBS J. 2023 Dec;290(24):5811-5834. doi: 10.1111/febs.16946. Epub 2023 Sep 7. PubMed |
| Notch intracellular domains form transcriptionally active heterodimeric complexes on sequence-paired sites. Gazdik TR, Crow JJ, Lawton T, Munroe CJ, Theriault H, Wood TM, Albig AR. Sci Rep. 2024 Jan 2;14(1):218. doi: 10.1038/s41598-023-50763-4. PubMed |
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