pcDNA4-Chk1-Flag Citations (7)

Originally described in: The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement.
Unsal-Kacmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK Mol Cell Biol. 2007 Apr . 27(8):3131-42. PubMed Journal

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Articles Citing pcDNA4-Chk1-Flag

Articles
Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. Mohni KN, Dee AR, Smith S, Schumacher AJ, Weller SK. J Virol. 2013 Jan;87(1):531-42. doi: 10.1128/JVI.02504-12. Epub 2012 Oct 24. PubMed
E1a promotes c-Myc-dependent replicative stress: implications in glioblastoma radiosensitization. Valero ML, Cimas FJ, Arias L, Melgar-Rojas P, Garcia E, Callejas-Valera JL, Garcia-Cano J, Serrano-Oviedo L, de la Cruz-Morcillo MA, Sanchez-Perez I, Sanchez-Prieto R. Cell Cycle. 2014;13(1):52-61. doi: 10.4161/cc.26754. Epub 2013 Oct 11. PubMed
Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons. Best A, James K, Dalgliesh C, Hong E, Kheirolahi-Kouhestani M, Curk T, Xu Y, Danilenko M, Hussain R, Keavney B, Wipat A, Klinck R, Cowell IG, Cheong Lee K, Austin CA, Venables JP, Chabot B, Santibanez Koref M, Tyson-Capper A, Elliott DJ. Nat Commun. 2014 Sep 11;5:4760. doi: 10.1038/ncomms5760. PubMed
Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells. Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Rossmann L, Bastians H, Concin N, Moll UM, Dobbelstein M. Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.124. PubMed
An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication. Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E, Watkins SC, Bakkenist CJ. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13374-13383. doi: 10.1073/pnas.1903418116. Epub 2019 Jun 17. PubMed
HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Moses N, Zhang M, Wu JY, Hu C, Xiang S, Geng X, Chen Y, Bai W, Zhang YW, Bepler G, Zhang XM. Cells. 2020 Oct 4;9(10). pii: cells9102237. doi: 10.3390/cells9102237. PubMed
ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization. Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings JR, Harris M, Muruganand A, Pyaram K, Miklja Z, Reiber M, Garcia T, Tran D, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor MA, Venneti S, Meeker AK, Huse JT, Morgan MA, Lowenstein PR, Castro MG, Yadav VN, Koschmann C. Cell Rep. 2022 Jan 11;38(2):110216. doi: 10.1016/j.celrep.2021.110216. PubMed

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