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pcDNA3.1-300(HAT-) Citations (11)

Originally described in: Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.
Chen LF, Mu Y, Greene WC EMBO J. 2002 Dec 2. 21(23):6539-48.
PubMed Journal

Articles Citing pcDNA3.1-300(HAT-)

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes. He H, Yu FX, Sun C, Luo Y. PLoS One. 2011;6(7):e22088. doi: 10.1371/journal.pone.0022088. Epub 2011 Jul 15. PubMed
Distinct roles for CBP and p300 on the RA-mediated expression of the meiosis commitment gene Stra8 in mouse embryonic stem cells. Chen W, Jia W, Wang K, Si X, Zhu S, Duan T, Kang J. PLoS One. 2013 Jun 13;8(6):e66076. doi: 10.1371/journal.pone.0066076. Print 2013. PubMed
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA. Nat Biotechnol. 2015 May;33(5):510-7. doi: 10.1038/nbt.3199. Epub 2015 Apr 6. PubMed

Associated Plasmids

Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression. Ogiwara H, Sasaki M, Mitachi T, Oike T, Higuchi S, Tominaga Y, Kohno T. Cancer Discov. 2016 Apr;6(4):430-45. doi: 10.1158/2159-8290.CD-15-0754. Epub 2015 Nov 24. PubMed
Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity. Pasquel D, Doricakova A, Li H, Kortagere S, Krasowski MD, Biswas A, Walton WG, Redinbo MR, Dvorak Z, Mani S. Biochim Biophys Acta. 2016 Sep;1859(9):1155-69. doi: 10.1016/j.bbagrm.2016.01.006. Epub 2016 Feb 23. PubMed
Wnt/beta-catenin-dependent acetylation of Pygo2 by CBP/p300 histone acetyltransferase family members. Andrews PG, Kao KR. Biochem J. 2016 Nov 15;473(22):4193-4203. Epub 2016 Sep 19. PubMed
Histone modifications affect differential regulation of TGFbeta- induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53. Boudreau HE, Ma WF, Korzeniowska A, Park JJ, Bhagwat MA, Leto TL. Oncotarget. 2017 Jul 4;8(27):44379-44397. doi: 10.18632/oncotarget.17892. PubMed
Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. Sacta MA, Tharmalingam B, Coppo M, Rollins DA, Deochand DK, Benjamin B, Yu L, Zhang B, Hu X, Li R, Chinenov Y, Rogatsky I. Elife. 2018 Feb 9;7. pii: 34864. doi: 10.7554/eLife.34864. PubMed
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Son SM, Park SJ, Lee H, Siddiqi F, Lee JE, Menzies FM, Rubinsztein DC. Cell Metab. 2019 Jan 8;29(1):192-201.e7. doi: 10.1016/j.cmet.2018.08.013. Epub 2018 Sep 6. PubMed

Associated Plasmids

EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer. Mahmud Z, Gomes AR, Lee HJ, Aimjongjun S, Jiramongkol Y, Yao S, Zona S, Alasiri G, Gong G, Yague E, Lam EW. Cancers (Basel). 2019 Jul 28;11(8). pii: cancers11081067. doi: 10.3390/cancers11081067. PubMed
p300 mediates the histone acetylation of ORMDL3 to affect airway inflammation and remodeling in asthma. Cheng Q, Shang Y, Huang W, Zhang Q, Li X, Zhou Q. Int Immunopharmacol. 2019 Nov;76:105885. doi: 10.1016/j.intimp.2019.105885. Epub 2019 Sep 16. PubMed

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