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pDONR223-RAF1 Citations (5)

Originally described in: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA Nature. 2010 Nov 24. ():.
PubMed Journal

Articles Citing pDONR223-RAF1

Articles
Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33. Azoitei N, Hoffmann CM, Ellegast JM, Ball CR, Obermayer K, Gossele U, Koch B, Faber K, Genze F, Schrader M, Kestler HA, Dohner H, Chiosis G, Glimm H, Frohling S, Scholl C. J Exp Med. 2012 Apr 9;209(4):697-711. doi: 10.1084/jem.20111910. Epub 2012 Mar 26. PubMed
HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization. Azoitei N, Diepold K, Brunner C, Rouhi A, Genze F, Becher A, Kestler H, van Lint J, Chiosis G, Koren J 3rd, Frohling S, Scholl C, Seufferlein T. Cancer Res. 2014 Dec 1;74(23):7125-36. doi: 10.1158/0008-5472.CAN-14-1017. Epub 2014 Oct 8. PubMed
Inhibition of RAS activation due to a homozygous ezrin variant in patients with profound intellectual disability. Riecken LB, Tawamie H, Dornblut C, Buchert R, Ismayel A, Schulz A, Schumacher J, Sticht H, Pohl KJ, Cui Y, Reis A, Morrison H, Abou Jamra R. Hum Mutat. 2015 Feb;36(2):270-8. doi: 10.1002/humu.22737. PubMed

Associated Plasmids

Imaging the rapid yet transient accumulation of regulatory lipids, lipid kinases, and protein kinases during membrane fusion, at sites of exocytosis of MMP-9 in MCF-7 cells. Stephens DC, Powell TW, Taraska JW, Harris DA. Lipids Health Dis. 2020 Aug 23;19(1):195. doi: 10.1186/s12944-020-01374-9. PubMed
Raf1 promotes successful Human Cytomegalovirus replication and is regulated by AMPK-mediated phosphorylation during infection. Dunn DM, Pack LJ, Munger JC. bioRxiv [Preprint]. 2023 Jul 26:2023.07.26.550702. doi: 10.1101/2023.07.26.550702. PubMed

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