Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pCMV-myc-Atg5 Citations (11)

Originally described in: A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.
Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T Proc Natl Acad Sci U S A. 2008 Mar 4. 105(9):3374-9.
PubMed Journal

Articles Citing pCMV-myc-Atg5

Articles
Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling. Zou M, Lu N, Hu C, Liu W, Sun Y, Wang X, You Q, Gu C, Xi T, Guo Q. Cell Signal. 2012 Aug;24(8):1722-32. doi: 10.1016/j.cellsig.2012.04.009. Epub 2012 Apr 25. PubMed
Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, Gao Q, Debatin KM, Beltinger C, Wei J. J Virol. 2014 May;88(9):5152-64. doi: 10.1128/JVI.03851-13. Epub 2014 Feb 26. PubMed
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells. Zhao X, Fang Y, Yang Y, Qin Y, Wu P, Wang T, Lai H, Meng L, Wang D, Zheng Z, Lu X, Zhang H, Gao Q, Zhou J, Ma D. Autophagy. 2015 Oct 3;11(10):1849-63. doi: 10.1080/15548627.2015.1017185. PubMed
Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M. Elife. 2016 Jan 26;5. pii: e12245. doi: 10.7554/eLife.12245. PubMed

Associated Plasmids

An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. Yan J, Hedl M, Abraham C. J Clin Invest. 2017 Jun 1;127(6):2192-2205. doi: 10.1172/JCI86282. Epub 2017 Apr 24. PubMed
Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling. Wang L, Guo W, Ma J, Dai W, Liu L, Guo S, Chen J, Wang H, Yang Y, Yi X, Wang G, Gao T, Zhu G, Li C. Autophagy. 2018;14(3):518-533. doi: 10.1080/15548627.2017.1384886. Epub 2017 Dec 31. PubMed
IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and IRF5 Immune-Mediated Disease Risk Variants Modulate This Outcome. Hedl M, Yan J, Witt H, Abraham C. J Immunol. 2019 Feb 1;202(3):920-930. doi: 10.4049/jimmunol.1800226. Epub 2018 Dec 28. PubMed
HIF1alpha promotes prostate cancer progression by increasing ATG5 expression. Yu K, Xiang L, Li S, Wang S, Chen C, Mu H. Anim Cells Syst (Seoul). 2019 Aug 28;23(5):326-334. doi: 10.1080/19768354.2019.1658637. eCollection 2019. PubMed
Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation. Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Gastroenterology. 2020 Jul 18. pii: S0016-5085(20)34953-2. doi: 10.1053/j.gastro.2020.07.024. PubMed
TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Sun R, Hedl M, Abraham C. Cell Mol Gastroenterol Hepatol. 2021;11(1):249-272. doi: 10.1016/j.jcmgh.2020.08.003. Epub 2020 Aug 19. PubMed
Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages. Wu M, An R, Zhou N, Chen Y, Cai H, Yan Q, Wang R, Luo Q, Yu L, Chen L, Du J. Front Immunol. 2022 Jun 10;13:905142. doi: 10.3389/fimmu.2022.905142. eCollection 2022. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.