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PLCG2-P522R
(Plasmid #254918)

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This material is available to academics and nonprofits only.
Item Catalog # Description Quantity Price (USD)
Plasmid 254918 Standard format: Plasmid sent in bacteria as agar stab 1 $94
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Backbone

  • Vector backbone
    pUC57
  • Backbone size w/o insert (bp) 4121
  • Vector type
    Mammalian Expression, CRISPR

Growth in Bacteria

  • Bacterial Resistance(s)
    Ampicillin, 100 μg/mL
  • Growth Temperature
    37°C
  • Growth Strain(s)
    DH5alpha
  • Copy number
    Unknown

Gene/Insert

  • Gene/Insert name
    phospholipase C gamma 2 - P522R
  • Alt name
    PLCG2 - P522R
  • gRNA/shRNA sequence
    CCCAAAATGTAGTTCTGTAG
  • Species
    H. sapiens (human)
  • Entrez Gene
    PLCG2 (a.k.a. APLAID, FCAS3, PLC-IV, PLC-gamma-2)

Resource Information

Terms and Licenses

  • Academic/Nonprofit Terms
  • Industry Terms
    • Not Available to Industry

Trademarks:

  • Zeocin® is an InvivoGen trademark.
How to cite this plasmid ( Back to top)

These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    PLCG2-P522R was a gift from Jason Meyer (Addgene plasmid # 254918 ; http://n2t.net/addgene:254918 ; RRID:Addgene_254918)

  • For your References section:

    Alzheimer's disease-associated PLCG2 variants alter microglial state and function in human induced pluripotent stem cell-derived microglia-like cells. Bedford LM, Tutrow KD, Hooper K, Messenger EJ, Hernandez M, Lamb BT, Meyer JS, Richardson TI, Bissel SJ. Alzheimers Dement. 2025 Oct;21(10):e70772. doi: 10.1002/alz.70772. 10.1002/alz.70772 PubMed 41066163
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