pCMV5 WT KSR1 Citations (4)
Originally described in: Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors.Joneson T, Fulton JA, Volle DJ, Chaika OV, Bar-Sagi D, Lewis RE J Biol Chem. 1998 Mar 27. 273(13):7743-8. PubMed Journal
Articles Citing pCMV5 WT KSR1
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| Deficient angiogenesis in redox-dead Cys17Ser PKARIalpha knock-in mice. Burgoyne JR, Rudyk O, Cho HJ, Prysyazhna O, Hathaway N, Weeks A, Evans R, Ng T, Schroder K, Brandes RP, Shah AM, Eaton P. Nat Commun. 2015 Aug 10;6:7920. doi: 10.1038/ncomms8920. PubMed |
| Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling. Dhawan NS, Scopton AP, Dar AC. Nature. 2016 Sep 1;537(7618):112-116. doi: 10.1038/nature19327. Epub 2016 Aug 24. PubMed |
| Structural basis for the action of the drug trametinib at KSR-bound MEK. Khan ZM, Real AM, Marsiglia WM, Chow A, Duffy ME, Yerabolu JR, Scopton AP, Dar AC. Nature. 2020 Dec;588(7838):509-514. doi: 10.1038/s41586-020-2760-4. Epub 2020 Sep 14. PubMed |
A biotin targeting chimera (BioTAC) system to map small molecule interactomes in situ.
Tao AJ, Jiang J, Gadbois GE, Goyal P, Boyle BT, Mumby EJ, Myers SA, English JG, Ferguson FM.
Nat Commun. 2023 Dec 4;14(1):8016. doi: 10.1038/s41467-023-43507-5.
PubMed
Associated Plasmids |
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