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pLentiCRISPRV2-humanLRRC8A
(Plasmid #261930)

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This material is available to academics and nonprofits only.
Item Catalog # Description Quantity Price (USD)
Plasmid 261930 Standard format: Plasmid sent in bacteria as agar stab 1 $94
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Backbone

  • Vector backbone
    pLentiCRISPRV2
  • Backbone manufacturer
    Feng Zhang (Addgene #52961)
  • Vector type
    Lentiviral

Growth in Bacteria

  • Bacterial Resistance(s)
    Ampicillin, 100 μg/mL
  • Growth Temperature
    37°C
  • Growth Strain(s)
    NEB Stable
  • Copy number
    High Copy

Gene/Insert

  • Gene/Insert name
    LRRC8A
  • gRNA/shRNA sequence
    ACCAAGTCACGGATCGAGCA
  • Species
    H. sapiens (human)
  • Entrez Gene
    LRRC8A (a.k.a. AGM5, HsLRRC8A, LRRC8, SWELL1)
  • Promoter EFS-NS

Cloning Information

  • Cloning method Restriction Enzyme
  • 5′ cloning site Unspecified (unknown if destroyed)

Terms and Licenses

  • Academic/Nonprofit Terms
  • Industry Terms
    • Not Available to Industry

Trademarks:

  • Zeocin® is an InvivoGen trademark.
How to cite this plasmid ( Back to top)

These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    pLentiCRISPRV2-humanLRRC8A was a gift from Jonathan Kagan (Addgene plasmid # 261930 ; http://n2t.net/addgene:261930 ; RRID:Addgene_261930)

  • For your References section:

    Purine and pyrimidine-based bacterial cyclic dinucleotides egress the phagosome and activate the innate immune sensor STING. Ragland SA, Lindblad KE, Li Y, Choi JH, Okin D, Mao JQ, Richmond-Buccola D, Coronado DR, Brown MR, Snapper SB, Kranzusch PJ, Kagan JC. Immunity. 2026 Aug 11;59(8):2086-2105.e17. doi: 10.1016/j.immuni.2026.06.023. Epub 2026 Jul 17. 10.1016/j.immuni.2026.06.023 PubMed 42468529
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