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EGFR-GFP Citations (43)

Plasmid Article: Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera.
Carter RE, Sorkin A J Biol Chem. 1998 Dec 25;273(52):35000-7.
PubMed Journal

Articles Citing EGFR-GFP

Combined targeting of PDK1 and EGFR triggers regression of glioblastoma by reversing the Warburg effect. Velpula KK, Bhasin A, Asuthkar S, Tsung AJ. Cancer Res. 2013 Dec 15;73(24):7277-89. doi: 10.1158/0008-5472.CAN-13-1868. Epub 2013 Oct 22. PubMed
Cell-derived vesicles for single-molecule imaging of membrane proteins. Moonschi FH, Effinger AK, Zhang X, Martin WE, Fox AM, Heidary DK, DeRouchey JE, Richards CI. Angew Chem Int Ed Engl. 2015 Jan 7;54(2):481-4. doi: 10.1002/anie.201408707. Epub 2014 Oct 31. PubMed
Unexpected requirement for a binding partner of the syntaxin family in phagocytosis by murine testicular Sertoli cells. Dong YS, Hou WG, Li Y, Liu DB, Hao GZ, Zhang HF, Li JC, Zhao J, Zhang S, Liang GB, Li W. Cell Death Differ. 2015 Oct 23. doi: 10.1038/cdd.2015.139. PubMed
EGFR/MDM2 signaling promotes NF-kappaB activation via PPARgamma degradation. Xu Y, Jin J, Zhang W, Zhang Z, Gao J, Liu Q, Zhou C, Xu Q, Shi H, Hou Y, Shi J. Carcinogenesis. 2015 Dec 30. pii: bgv252. PubMed
Multifunctional Transmembrane Protein Ligands for Cell-Specific Targeting of Plasma Membrane-Derived Vesicles. Zhao C, Busch DJ, Vershel CP, Stachowiak JC. Small. 2016 Jul;12(28):3837-48. doi: 10.1002/smll.201600493. Epub 2016 Jun 13. PubMed
Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases. Sommer AK, Hermawan A, Mickler FM, Ljepoja B, Knyazev P, Brauchle C, Ullrich A, Wagner E, Roidl A. Oncotarget. 2016 Aug 2;7(31):50461-50476. doi: 10.18632/oncotarget.10459. PubMed
Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte-Duclos disease. Colby S, Yehia L, Niazi F, Chen J, Ni Y, Mester JL, Eng C. Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001230. PubMed
Heparin-binding epidermal growth factor-like growth factor promotes neuroblastoma differentiation. Gaviglio AL, Knelson EH, Blobe GC. FASEB J. 2017 May;31(5):1903-1915. doi: 10.1096/fj.201600828R. Epub 2017 Feb 7. PubMed
EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Vaishnavi A, Schubert L, Rix U, Marek LA, Le AT, Keysar SB, Glogowska MJ, Smith MA, Kako S, Sumi NJ, Davies KD, Ware KE, Varella-Garcia M, Haura EB, Jimeno A, Heasley LE, Aisner DL, Doebele RC. Cancer Res. 2017 Jul 1;77(13):3551-3563. doi: 10.1158/0008-5472.CAN-17-0109. Epub 2017 Apr 20. PubMed
The ErbB family and androgen receptor signaling are targets of Celecoxib in prostate cancer. Brizzolara A, Benelli R, Vene R, Barboro P, Poggi A, Tosetti F, Ferrari N. Cancer Lett. 2017 Aug 1;400:9-17. doi: 10.1016/j.canlet.2017.04.025. Epub 2017 Apr 25. PubMed
EGFR and HER2 activate rigidity sensing only on rigid matrices. Saxena M, Liu S, Yang B, Hajal C, Changede R, Hu J, Wolfenson H, Hone J, Sheetz MP. Nat Mater. 2017 Jul;16(7):775-781. doi: 10.1038/nmat4893. Epub 2017 May 1. PubMed
w09, a novel autophagy enhancer, induces autophagy-dependent cell apoptosis via activation of the EGFR-mediated RAS-RAF1-MAP2K-MAPK1/3 pathway. Zhang P, Zheng Z, Ling L, Yang X, Zhang N, Wang X, Hu M, Xia Y, Ma Y, Yang H, Wang Y, Liu H. Autophagy. 2017 Jul 3;13(7):1093-1112. doi: 10.1080/15548627.2017.1319039. Epub 2017 May 17. PubMed
Real-Time Sensing of Single-Ligand Delivery with Nanoaperture-Integrated Microfluidic Devices. Martin WE, Ge N, Srijanto BR, Furnish E, Collier CP, Trinkle CA, Richards CI. ACS Omega. 2017 Jul 31;2(7):3858-3867. doi: 10.1021/acsomega.7b00934. Epub 2017 Jul 25. PubMed
Sortilin limits EGFR signaling by promoting its internalization in lung cancer. Al-Akhrass H, Naves T, Vincent F, Magnaudeix A, Durand K, Bertin F, Melloni B, Jauberteau MO, Lalloue F. Nat Commun. 2017 Oct 30;8(1):1182. doi: 10.1038/s41467-017-01172-5. PubMed
Induction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis. Taute S, Pfister HJ, Steger G. Front Microbiol. 2017 Nov 10;8:2197. doi: 10.3389/fmicb.2017.02197. eCollection 2017. PubMed
A small protein probe for correlated microscopy of endogenous proteins. de Beer MA, Kuipers J, van Bergen En Henegouwen PMP, Giepmans BNG. Histochem Cell Biol. 2018 Mar;149(3):261-268. doi: 10.1007/s00418-018-1632-6. Epub 2018 Jan 11. PubMed

Associated Plasmids

Comparison between iMSD and 2D-pCF analysis for molecular motion studies on in vivo cells: The case of the epidermal growth factor receptor. Malacrida L, Rao E, Gratton E. Methods. 2018 May 1;140-141:74-84. doi: 10.1016/j.ymeth.2018.01.010. Epub 2018 Mar 1. PubMed
IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, Chida K, Weghuber J, Hakuno F, Takahashi SI. Elife. 2018 Apr 11;7. pii: 32893. doi: 10.7554/eLife.32893. PubMed
Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy. Ardelt MA, Frohlich T, Martini E, Muller M, Kanitz V, Atzberger C, Cantonati P, Messner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, Konig L, Parazzoli D, Zahler S, Rothenfusser S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J. Hepatology. 2019 Jan;69(1):376-393. doi: 10.1002/hep.30190. Epub 2018 Dec 22. PubMed
TGF3L fusion enhances the antitumor activity of TRAIL by promoting assembly into polymers. Wang Y, Lei Q, Yan Z, Shen C, Wang N. Biochem Pharmacol. 2018 Sep;155:510-523. doi: 10.1016/j.bcp.2018.07.035. Epub 2018 Jul 29. PubMed
RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation. Ho SR, Lin WC. J Biol Chem. 2018 Oct 19;293(42):16307-16323. doi: 10.1074/jbc.RA118.002887. Epub 2018 Aug 31. PubMed
Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures. Baschieri F, Dayot S, Elkhatib N, Ly N, Capmany A, Schauer K, Betz T, Vignjevic DM, Poincloux R, Montagnac G. Nat Commun. 2018 Sep 20;9(1):3825. doi: 10.1038/s41467-018-06367-y. PubMed
Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis. Williams KC, Cepeda MA, Javed S, Searle K, Parkins KM, Makela AV, Hamilton AM, Soukhtehzari S, Kim Y, Tuck AB, Ronald JA, Foster PJ, Chambers AF, Leong HS. Oncogene. 2019 May;38(19):3598-3615. doi: 10.1038/s41388-018-0667-4. Epub 2019 Jan 16. PubMed
The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors. Sakai R, Fukuda R, Unida S, Aki M, Ono Y, Endo A, Kusumi S, Koga D, Fukushima T, Komada M, Okiyoneda T. J Cell Sci. 2019 Feb 7;132(3). pii: jcs.228007. doi: 10.1242/jcs.228007. PubMed
Slowly Reducible Genetically Encoded Green Fluorescent Indicator for In Vivo and Ex Vivo Visualization of Hydrogen Peroxide. Subach OM, Kunitsyna TA, Mineyeva OA, Lazutkin AA, Bezryadnov DV, Barykina NV, Piatkevich KD, Ermakova YG, Bilan DS, Belousov VV, Anokhin KV, Enikolopov GN, Subach FV. Int J Mol Sci. 2019 Jun 27;20(13). pii: ijms20133138. doi: 10.3390/ijms20133138. PubMed
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Lundby A, Franciosa G, Emdal KB, Refsgaard JC, Gnosa SP, Bekker-Jensen DB, Secher A, Maurya SR, Paul I, Mendez BL, Kelstrup CD, Francavilla C, Kveiborg M, Montoya G, Jensen LJ, Olsen JV. Cell. 2019 Oct 3;179(2):543-560.e26. doi: 10.1016/j.cell.2019.09.008. PubMed
Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration. Kostelnik KB, Barker A, Schultz C, Mitchell TP, Rajeeve V, White IJ, Aurrand-Lions M, Nourshargh S, Cutillas P, Nightingale TD. PLoS Biol. 2019 Dec 2;17(12):e3000554. doi: 10.1371/journal.pbio.3000554. eCollection 2019 Dec. PubMed
Fabrication, Characterization and Application of Biomolecule Micropatterns on Cyclic Olefin Polymer (COP) Surfaces with Adjustable Contrast. Hager R, Haselgrubler T, Haas S, Lipp AM, Weghuber J. Biosensors (Basel). 2019 Dec 28;10(1). pii: bios10010003. doi: 10.3390/bios10010003. PubMed
The Relative Permittivity Changes of EGF by 50 Hz MF Exposure Neither Affect the Interaction of EGF With EGFR Nor Its Biological Effects. Fei Y, Jin Y, Zhao X, Wang Y, Qian J, Su L, Chen G. Bioelectromagnetics. 2020 Apr;41(3):241-246. doi: 10.1002/bem.22249. Epub 2020 Jan 17. PubMed
Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors. Chin TM, Boopathy GTK, Man EPS, Clohessy JG, Csizmadia E, Quinlan MP, Putti T, Wan SC, Xie C, Ali A, Wai FC, Ong YS, Goh BC, Settleman J, Hong W, Levantini E, Tenen DG. Theranostics. 2020 Feb 3;10(6):2727-2743. doi: 10.7150/thno.38729. eCollection 2020. PubMed
Effect of Erufosine on Membrane Lipid Order in Breast Cancer Cell Models. Tzoneva R, Stoyanova T, Petrich A, Popova D, Uzunova V, Momchilova A, Chiantia S. Biomolecules. 2020 May 22;10(5). pii: biom10050802. doi: 10.3390/biom10050802. PubMed

Associated Plasmids

Deficiency of GABARAP but not its Paralogs Causes Enhanced EGF-induced EGFR Degradation. Dobner J, Simons IM, Rufinatscha K, Hansch S, Schwarten M, Weiergraber OH, Abdollahzadeh I, Gensch T, Bode JG, Hoffmann S, Willbold D. Cells. 2020 May 22;9(5). pii: cells9051296. doi: 10.3390/cells9051296. PubMed
Frustration of endocytosis potentiates compression-induced receptor signaling. Baschieri F, Le Devedec D, Tettarasar S, Elkhatib N, Montagnac G. J Cell Sci. 2020 Sep 1;133(17). pii: jcs.239681. doi: 10.1242/jcs.239681. PubMed
Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth. Hu L, Shen D, Liang D, Shi J, Song C, Jiang K, Menglin Ren, Du S, Cheng W, Ma J, Li S, Bi X, Barr MP, Fang Z, Xu Q, Li W, Piao H, Meng S. Cancer Lett. 2020 Nov 28;493:156-166. doi: 10.1016/j.canlet.2020.08.023. Epub 2020 Aug 27. PubMed
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth. Yao N, Wang CR, Liu MQ, Li YJ, Chen WM, Li ZQ, Qi Q, Lu JJ, Fan CL, Chen MF, Qi M, Li XB, Hong J, Zhang DM, Ye WC. Signal Transduct Target Ther. 2020 Oct 9;5(1):214. doi: 10.1038/s41392-020-00251-2. PubMed
High-Precision Protein-Tracking With Interferometric Scattering Microscopy. Taylor RW, Holler C, Mahmoodabadi RG, Kuppers M, Dastjerdi HM, Zaburdaev V, Schambony A, Sandoghdar V. Front Cell Dev Biol. 2020 Nov 3;8:590158. doi: 10.3389/fcell.2020.590158. eCollection 2020. PubMed
Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma. Akhavanfard S, Yehia L, Padmanabhan R, Reynolds JP, Ni Y, Eng C. Hum Mol Genet. 2021 Jan 21;29(22):3679-3690. doi: 10.1093/hmg/ddaa268. PubMed
Phosphorylation of REPS1 at Ser709 by RSK attenuates the recycling of transferrin receptor. Kim SH, Cho JH, Park BO, Park BC, Kim JH, Park SG, Kim S. BMB Rep. 2021 May;54(5):272-277. PubMed
UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling. Torrino S, Tiroille V, Dolfi B, Dufies M, Hinault C, Bonesso L, Dagnino S, Uhler J, Irondelle M, Gay AS, Fleuriot L, Debayle D, Lacas-Gervais S, Cormont M, Bertero T, Bost F, Gilleron J, Clavel S. Elife. 2021 Apr 22;10. pii: 68348. doi: 10.7554/eLife.68348. PubMed
alpha7 Nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension. Vang A, da Silva Goncalves Bos D, Fernandez-Nicolas A, Zhang P, Morrison AR, Mancini TJ, Clements RT, Polina I, Cypress MW, Jhun BS, Hawrot E, Mende U, O-Uchi J, Choudhary G. JCI Insight. 2021 Jun 22;6(12). pii: 142945. doi: 10.1172/jci.insight.142945. PubMed
Mechanism of p38 MAPK-induced EGFR endocytosis and its crosstalk with ligand-induced pathways. Perez Verdaguer M, Zhang T, Paulo JA, Gygi S, Watkins SC, Sakurai H, Sorkin A. J Cell Biol. 2021 Jul 5;220(7). pii: 212181. doi: 10.1083/jcb.202102005. Epub 2021 May 25. PubMed
Structural organization and dynamics of FCHo2 docking on membranes. El Alaoui F, Casuso I, Sanchez-Fuentes D, Arpin-Andre C, Rathar R, Baecker V, Castro A, Lorca T, Viaud J, Vassilopoulos S, Carretero-Genevrier A, Picas L. Elife. 2022 Jan 19;11. pii: 73156. doi: 10.7554/eLife.73156. PubMed
Human C1orf27 protein interacts with alpha2A-adrenergic receptor and regulates its anterograde transport. Xu X, Wu G. J Biol Chem. 2022 Jun;298(6):102021. doi: 10.1016/j.jbc.2022.102021. Epub 2022 May 10. PubMed

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