pQCXIH-Myc-YAP Citations (25)
Originally described in: Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL Genes Dev. 2007 Nov 1. 21(21):2747-61. PubMed Journal
Articles Citing pQCXIH-Myc-YAP
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| YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead-dependent manner. Han D, Byun SH, Park S, Kim J, Kim I, Ha S, Kwon M, Yoon K. Biochem Biophys Res Commun. 2015 Feb 27;458(1):110-6. doi: 10.1016/j.bbrc.2015.01.077. Epub 2015 Jan 26. PubMed |
| Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells. Basu-Roy U, Bayin NS, Rattanakorn K, Han E, Placantonakis DG, Mansukhani A, Basilico C. Nat Commun. 2015 Apr 2;6:6411. doi: 10.1038/ncomms7411. PubMed |
| Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations. Troilo A, Benson EK, Esposito D, Garibsingh RA, Reddy EP, Mungamuri SK, Aaronson SA. Oncotarget. 2016 Apr 29. doi: 10.18632/oncotarget.9117. PubMed |
| Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventela S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen PL, Joensuu H, Grenman R, Ivaska J. Nat Commun. 2016 Aug 4;7:12237. doi: 10.1038/ncomms12237. PubMed |
| Restoration of YAP activation rescues HL-1 cardiomyocytes from apoptotic death by ethanol. Noritake K, Aki T, Kimura M, Funakoshi T, Unuma K, Uemura K. J Toxicol Sci. 2017;42(5):545-551. doi: 10.2131/jts.42.545. PubMed |
| RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer. Kulkarni M, Tan TZ, Syed Sulaiman NB, Lamar JM, Bansal P, Cui J, Qiao Y, Ito Y. Oncotarget. 2018 Feb 6;9(18):14175-14192. doi: 10.18632/oncotarget.24419. eCollection 2018 Mar 6. PubMed |
| YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1alpha. Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T. Microvasc Res. 2018 Sep;119:73-83. doi: 10.1016/j.mvr.2018.04.003. Epub 2018 Apr 20. PubMed |
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.
Er EE, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti FG, Schachner M, Malladi S, Massague J.
Nat Cell Biol. 2018 Aug;20(8):966-978. doi: 10.1038/s41556-018-0138-8. Epub 2018 Jul 23.
PubMed
Associated Plasmids |
| Loss of VGLL4 suppresses tumor PD-L1 expression and immune evasion. Wu A, Wu Q, Deng Y, Liu Y, Lu J, Liu L, Li X, Liao C, Zhao B, Song H. EMBO J. 2019 Jan 3;38(1). pii: embj.201899506. doi: 10.15252/embj.201899506. Epub 2018 Nov 5. PubMed |
| OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ. Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, Feng XH, Guan KL, Zhang L. Mol Cell. 2019 Jan 3;73(1):7-21.e7. doi: 10.1016/j.molcel.2018.10.030. Epub 2018 Nov 21. PubMed |
| Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A. Aging (Albany NY). 2019 Sep 5;11(17):7051-7069. doi: 10.18632/aging.102236. Epub 2019 Sep 5. PubMed |
| Non-cell autonomous promotion of astrogenesis at late embryonic stages by constitutive YAP activation. Han D, Kwon M, Lee SM, Pleasure SJ, Yoon K. Sci Rep. 2020 Apr 27;10(1):7041. doi: 10.1038/s41598-020-63890-z. PubMed |
| Yes-Associated Protein Enhances Fibroblast Growth Factor 2-Dependent Neural Stem Cell Proliferation by Induction of Fibroblast Growth Factor Receptor Expression. Han D, Lee SM, Kwon M, Noh H, Lee JH, Yoon Y, Cho JY, Yoon K. Stem Cells Dev. 2020 Aug 12. doi: 10.1089/scd.2019.0281. PubMed |
| Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis. King B, Araki J, Palm W, Thompson CB. Genes Dev. 2020 Oct 1;34(19-20):1345-1358. doi: 10.1101/gad.340661.120. Epub 2020 Sep 10. PubMed |
| YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis. Feng Y, Zou R, Zhang X, Shen M, Chen X, Wang J, Niu W, Yuan Y, Yuan F. Angiogenesis. 2021 Jan 5. pii: 10.1007/s10456-020-09760-8. doi: 10.1007/s10456-020-09760-8. PubMed |
| Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase. Raghubir M, Azeem SM, Hasnat R, Rahman CN, Wong L, Yan S, Huang YQ, Zhagui R, Blyufer A, Tariq I, Tam C, Lhamo S, Cecilio L, Chowdhury Y, ChandThakuri S, Mahajan SS. Sci Rep. 2021 Oct 25;11(1):20974. doi: 10.1038/s41598-021-00439-8. PubMed |
| EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1. Ando T, Arang N, Wang Z, Costea DE, Feng X, Goto Y, Izumi H, Gilardi M, Ando K, Gutkind JS. Commun Biol. 2021 Nov 1;4(1):1237. doi: 10.1038/s42003-021-02744-4. PubMed |
| Human blastoids model blastocyst development and implantation. Kagawa H, Javali A, Khoei HH, Sommer TM, Sestini G, Novatchkova M, Scholte Op Reimer Y, Castel G, Bruneau A, Maenhoudt N, Lammers J, Loubersac S, Freour T, Vankelecom H, David L, Rivron N. Nature. 2022 Jan;601(7894):600-605. doi: 10.1038/s41586-021-04267-8. Epub 2021 Dec 2. PubMed |
| ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation. Esposito D, Pant I, Shen Y, Qiao RF, Yang X, Bai Y, Jin J, Poulikakos PI, Aaronson SA. Nat Commun. 2022 Feb 4;13(1):703. doi: 10.1038/s41467-022-28319-3. PubMed |
YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia.
Hatterschide J, Castagnino P, Kim HW, Sperry SM, Montone KT, Basu D, White EA.
Elife. 2022 Feb 16;11. pii: 75466. doi: 10.7554/eLife.75466.
PubMed
Associated Plasmids |
| YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth. Vaidyanathan S, Salmi TM, Sathiqu RM, McConville MJ, Cox AG, Brown KK. Dev Cell. 2022 Mar 28;57(6):719-731.e8. doi: 10.1016/j.devcel.2022.02.004. Epub 2022 Feb 24. PubMed |
| A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation. Drozdz MM, Doane AS, Alkallas R, Desman G, Bareja R, Reilly M, Bang J, Yusupova M, You J, Eraslan Z, Wang JZ, Verma A, Aguirre K, Kane E, Watson IR, Elemento O, Piskounova E, Merghoub T, Zippin JH. Cell Rep. 2022 Sep 27;40(13):111412. doi: 10.1016/j.celrep.2022.111412. PubMed |
| YAP inhibits HCMV replication by impairing STING-mediated nuclear transport of the viral genome. Lee JH, Kwon M, Lim WY, Yoo CR, Yoon Y, Han D, Ahn JH, Yoon K. PLoS Pathog. 2022 Dec 1;18(12):e1011007. doi: 10.1371/journal.ppat.1011007. eCollection 2022 Dec. PubMed |
| Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity. Ippolito F, Consalvi V, Noce V, Battistelli C, Cicchini C, Tripodi M, Amicone L, Marchetti A. Cell Death Dis. 2023 Jan 17;14(1):32. doi: 10.1038/s41419-023-05569-7. PubMed |
| AR activates YAP/TAZ differentially in prostate cancer. Salem O, Jia S, Qian BZ, Hansen CG. Life Sci Alliance. 2023 Jun 29;6(9):e202201620. doi: 10.26508/lsa.202201620. Print 2023 Sep. PubMed |
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