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pMJ841 Citations (8)

Originally described in: A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity.
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E Science. 2012 Aug 17;337(6096):816-21. doi: 10.1126/science.1225829. Epub 2012 Jun 28.
PubMed Journal

Articles Citing pMJ841

Articles
CRISPR RNA-guided activation of endogenous human genes. Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK. Nat Methods. 2013 Jul 25. doi: 10.1038/nmeth.2598. PubMed

Associated Plasmids

Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Anders C, Bargsten K, Jinek M. Mol Cell. 2016 Mar 17;61(6):895-902. doi: 10.1016/j.molcel.2016.02.020. PubMed
Sequence-specific m6A demethylation in RNA by FTO fused to RCas9. Rau K, Roesner L, Rentmeister A. RNA. 2019 Jul 1. pii: rna.070706.119. doi: 10.1261/rna.070706.119. PubMed
The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair. Mardenborough YSN, Nitsenko K, Laffeber C, Duboc C, Sahin E, Quessada-Vial A, Winterwerp HHK, Sixma TK, Kanaar R, Friedhoff P, Strick TR, Lebbink JHG. Nucleic Acids Res. 2019 Dec 16;47(22):11667-11680. doi: 10.1093/nar/gkz834. PubMed
Probing the stability of the SpCas9-DNA complex after cleavage. Aldag P, Welzel F, Jakob L, Schmidbauer A, Rutkauskas M, Fettes F, Grohmann D, Seidel R. Nucleic Acids Res. 2021 Dec 2;49(21):12411-12421. doi: 10.1093/nar/gkab1072. PubMed
Guide RNAs containing universal bases enable Cas9/Cas12a recognition of polymorphic sequences. Krysler AR, Cromwell CR, Tu T, Jovel J, Hubbard BP. Nat Commun. 2022 Mar 25;13(1):1617. doi: 10.1038/s41467-022-29202-x. PubMed
N(6)-methyladenosine methylation-regulated polo-like kinase 1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma. Tatekawa S, Tamari K, Chijimatsu R, Konno M, Motooka D, Mitsufuji S, Akita H, Kobayashi S, Murakumo Y, Doki Y, Eguchi H, Ishii H, Ogawa K. Sci Rep. 2022 Jun 30;12(1):11074. doi: 10.1038/s41598-022-15196-5. PubMed
Cas9 is mostly orthogonal to human systems of DNA break sensing and repair. Maltseva EA, Vasil'eva IA, Moor NA, Kim DV, Dyrkheeva NS, Kutuzov MM, Vokhtantsev IP, Kulishova LM, Zharkov DO, Lavrik OI. PLoS One. 2023 Nov 29;18(11):e0294683. doi: 10.1371/journal.pone.0294683. eCollection 2023. PubMed

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