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pCS2-UTX-F-MT2 Citations (5)

Originally described in: UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.
Wang C, Lee JE, Cho YW, Xiao Y, Jin Q, Liu C, Ge K Proc Natl Acad Sci U S A. 2012 Sep 4.
PubMed Journal

Articles Citing pCS2-UTX-F-MT2

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights AJ, Pardo M, Yu L, Choudhary JS, Metzakopian E, Iyer V, Yun H, Park N, Varela I, Bautista R, Collord G, Dovey O, Garyfallos DA, De Braekeleer E, Kondo S, Cooper J, Gottgens B, Bullinger L, Northcott PA, Adams D, Vassiliou GS, Huntly BJP. Nat Genet. 2018 Jun;50(6):883-894. doi: 10.1038/s41588-018-0114-z. Epub 2018 May 7. PubMed
X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism. Kaneko S, Li X. Sci Adv. 2018 Jun 13;4(6):eaar5598. doi: 10.1126/sciadv.aar5598. eCollection 2018 Jun. PubMed
UTX condensation underlies its tumour-suppressive activity. Shi B, Li W, Song Y, Wang Z, Ju R, Ulman A, Hu J, Palomba F, Zhao Y, Le JP, Jarrard W, Dimoff D, Digman MA, Gratton E, Zang C, Jiang H. Nature. 2021 Sep;597(7878):726-731. doi: 10.1038/s41586-021-03903-7. Epub 2021 Sep 15. PubMed
X chromosome factor Kdm6a enhances cognition independent of its demethylase function in the aging XY male brain. Shaw CK, Abdulai-Saiku S, Marino F, Wang D, Davis EJ, Panning B, Dubal DB. J Gerontol A Biol Sci Med Sci. 2023 Jan 9:glad007. doi: 10.1093/gerona/glad007. PubMed
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition. Boila LD, Ghosh S, Bandyopadhyay SK, Jin L, Murison A, Zeng AGX, Shaikh W, Bhowmik S, Muddineni SSNA, Biswas M, Sinha S, Chatterjee SS, Mbong N, Gan OI, Bose A, Chakraborty S, Arruda A, Kennedy JA, Mitchell A, Lechman ER, Banerjee D, Milyavsky M, Minden MD, Dick JE, Sengupta A. Leukemia. 2023 Jan 31. doi: 10.1038/s41375-023-01833-z. PubMed

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