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EGFP-alphasynuclein-WT Citations (26)

Originally described in: Alpha-synuclein overexpression promotes aggregation of mutant huntingtin.
Furlong RA, Narain Y, Rankin J, Wyttenbach A, Rubinsztein DC Biochem J. 2000 Mar 15;346 Pt 3:577-81.
PubMed Journal

Articles Citing EGFP-alphasynuclein-WT

Articles
Alpha-Synuclein Expression Restricts RNA Viral Infections in the Brain. Beatman EL, Massey A, Shives KD, Burrack KS, Chamanian M, Morrison TE, Beckham JD. J Virol. 2015 Dec 30;90(6):2767-82. doi: 10.1128/JVI.02949-15. PubMed
Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts. Emanuele M, Esposito A, Camerini S, Antonucci F, Ferrara S, Seghezza S, Catelani T, Crescenzi M, Marotta R, Canale C, Matteoli M, Menna E, Chieregatti E. EBioMedicine. 2016 May;7:191-204. doi: 10.1016/j.ebiom.2016.03.038. Epub 2016 Apr 5. PubMed
Analysis of sheep alpha-synuclein provides a molecular strategy for the reduction of fibrillation. Bickle L, Hopwood JJ, Karageorgos L. Biochim Biophys Acta. 2016 Dec 19;1865(3):261-273. doi: 10.1016/j.bbapap.2016.12.008. PubMed
alpha-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson's disease patients. Dieriks BV, Park TI, Fourie C, Faull RL, Dragunow M, Curtis MA. Sci Rep. 2017 Feb 23;7:42984. doi: 10.1038/srep42984. PubMed
Intra-articular lentivirus-mediated gene therapy targeting CRACM1 for the treatment of collagen-induced arthritis. Liu S, Kiyoi T, Takemasa E, Maeyama K. J Pharmacol Sci. 2017 Mar;133(3):130-138. doi: 10.1016/j.jphs.2017.02.001. Epub 2017 Feb 11. PubMed
A novel autophagy modulator 6-Bio ameliorates SNCA/alpha-synuclein toxicity. Suresh SN, Chavalmane AK, Dj V, Yarreiphang H, Rai S, Paul A, Clement JP, Alladi PA, Manjithaya R. Autophagy. 2017 Jul 3;13(7):1221-1234. doi: 10.1080/15548627.2017.1302045. Epub 2017 Mar 28. PubMed
Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda-Andoh T, Okano H, Nakashima K. Stem Cell Reports. 2017 Jun 6;8(6):1743-1756. doi: 10.1016/j.stemcr.2017.05.001. PubMed
Chromatographic HPV-16 E6/E7 plasmid vaccine purification employing L-histidine and 1-benzyl-L-histidine affinity ligands. Amorim LFA, Gaspar R, Pereira PC, Cernigoj U, Sousa F, Queiroz JA, Sousa A. Electrophoresis. 2017 Jul 6. doi: 10.1002/elps.201700147. PubMed
Glucosylsphingosine Promotes alpha-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease. Taguchi YV, Liu J, Ruan J, Pacheco J, Zhang X, Abbasi J, Keutzer J, Mistry PK, Chandra SS. J Neurosci. 2017 Oct 4;37(40):9617-9631. doi: 10.1523/JNEUROSCI.1525-17.2017. Epub 2017 Aug 28. PubMed
Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRalpha Is Neuroprotective. Suresh SN, Chavalmane AK, Pillai M, Ammanathan V, Vidyadhara DJ, Yarreiphang H, Rai S, Paul A, Clement JP, Alladi PA, Manjithaya R. Front Mol Neurosci. 2018 Apr 9;11:109. doi: 10.3389/fnmol.2018.00109. eCollection 2018. PubMed
Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models. Shaltouki A, Hsieh CH, Kim MJ, Wang X. Acta Neuropathol. 2018 Oct;136(4):607-620. doi: 10.1007/s00401-018-1873-4. Epub 2018 Jun 9. PubMed
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Mann JR, Gleixner AM, Mauna JC, Gomes E, DeChellis-Marks MR, Needham PG, Copley KE, Hurtle B, Portz B, Pyles NJ, Guo L, Calder CB, Wills ZP, Pandey UB, Kofler JK, Brodsky JL, Thathiah A, Shorter J, Donnelly CJ. Neuron. 2019 Feb 27. pii: S0896-6273(19)30075-3. doi: 10.1016/j.neuron.2019.01.048. PubMed
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, Hong Y, Ford C, Luo Y, Qi X. Acta Neuropathol. 2019 Jun;137(6):939-960. doi: 10.1007/s00401-019-01993-2. Epub 2019 Mar 15. PubMed
Poly-ADP-ribose assisted protein localization resolves that DJ-1, but not LRRK2 or alpha-synuclein, is localized to the mitochondrial matrix. Osuagwu N, Dolle C, Tzoulis C. PLoS One. 2019 Jul 19;14(7):e0219909. doi: 10.1371/journal.pone.0219909. eCollection 2019. PubMed
Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling. Mazzocchi M, Wyatt SL, Mercatelli D, Morari M, Morales-Prieto N, Collins LM, Sullivan AM, O'Keeffe GW. Front Cell Dev Biol. 2019 Sep 13;7:191. doi: 10.3389/fcell.2019.00191. eCollection 2019. PubMed
Hsp110 mitigates alpha-synuclein pathology in vivo. Taguchi YV, Gorenberg EL, Nagy M, Thrasher D, Fenton WA, Volpicelli-Daley L, Horwich AL, Chandra SS. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24310-24316. doi: 10.1073/pnas.1903268116. Epub 2019 Nov 4. PubMed
Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration. Sn S, Pandurangi J, Murumalla R, Dj V, Garimella L, Acharya A, Rai S, Paul A, Yarreiphang H, Pillai MS, Giridharan M, Clement JP, Alladi PA, Saiyed T, Manjithaya R. EBioMedicine. 2019 Dec;50:260-273. doi: 10.1016/j.ebiom.2019.10.036. Epub 2019 Nov 11. PubMed
The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations. Chen V, Moncalvo M, Tringali D, Tagliafierro L, Shriskanda A, Ilich E, Dong W, Kantor B, Chiba-Falek O. Hum Mol Genet. 2020 Nov 4;29(18):3107-3121. doi: 10.1093/hmg/ddaa183. PubMed
Anti-Na(+)/K(+)-ATPase immunotherapy ameliorates alpha-synuclein pathology through activation of Na(+)/K(+)-ATPase alpha1-dependent autophagy. Cao L, Xiong S, Wu Z, Ding L, Zhou Y, Sun H, Zhu M, Lee WT, Nie X, Bian JS. Sci Adv. 2021 Jan 27;7(5). pii: 7/5/eabc5062. doi: 10.1126/sciadv.abc5062. Print 2021 Jan. PubMed
Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration. Wang C, Lau CY, Ma F, Zheng C. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34). pii: 2106504118. doi: 10.1073/pnas.2106504118. PubMed
NME1 Protects Against Neurotoxin-, alpha-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson's Disease. Anantha J, Goulding SR, Tuboly E, O'Mahony AG, Moloney GM, Lomansey G, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. Mol Neurobiol. 2022 Jan;59(1):61-76. doi: 10.1007/s12035-021-02569-6. Epub 2021 Oct 8. PubMed
Lentiviral Vectors Expressing Chimeric NEDD4 Ubiquitin Ligases: An Innovative Approach for Interfering with Alpha-Synuclein Accumulation. Vogiatzis S, Celestino M, Trevisan M, Magro G, Del Vecchio C, Erdengiz D, Palu G, Parolin C, Maguire-Zeiss K, Calistri A. Cells. 2021 Nov 21;10(11). pii: cells10113256. doi: 10.3390/cells10113256. PubMed
Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against alpha-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells. McCarthy E, Barron A, Morales-Prieto N, Mazzocchi M, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. Mol Neurobiol. 2022 May;59(5):2745-2757. doi: 10.1007/s12035-022-02768-9. Epub 2022 Feb 17. PubMed
Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPalpha mutants causes lipofuscin accumulation. Lee J, Xu Y, Saidi L, Xu M, Zinsmaier K, Ye Y. Autophagy. 2022 May 4:1-20. doi: 10.1080/15548627.2022.2065618. PubMed
Sequestration of TDP-43(216-414) Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. Peinado JR, Chaplot K, Jarvela TS, Barbieri EM, Shorter J, Lindberg I. ACS Chem Neurosci. 2022 Jun 1;13(11):1651-1665. doi: 10.1021/acschemneuro.2c00156. Epub 2022 May 12. PubMed
Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons. Kulkarni VV, Stempel MH, Anand A, Sidibe DK, Maday S. J Neurosci. 2022 Nov 9;42(45):8524-8541. doi: 10.1523/JNEUROSCI.1292-22.2022. Epub 2022 Sep 27. PubMed

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