pCAG-hCas9 Citations (12)

Originally described in: Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system.
Horii T, Tamura D, Morita S, Kimura M, Hatada I Int J Mol Sci. 2013 Sep 30;14(10):19774-81. doi: 10.3390/ijms141019774. PubMed Journal

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Articles Citing pCAG-hCas9

Articles
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F. Nat Commun. 2016 Aug 24;7:12547. doi: 10.1038/ncomms12547. PubMed
Genome Editing of Mouse by Cytoplasmic Injection. Horii T, Hatada I. Methods Mol Biol. 2017;1630:55-66. doi: 10.1007/978-1-4939-7128-2_5. PubMed
Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation. Panaliappan TK, Wittmann W, Jidigam VK, Mercurio S, Bertolini JA, Sghari S, Bose R, Patthey C, Nicolis SK, Gunhaga L. Development. 2018 Jan 19;145(2). pii: 145/2/dev153791. doi: 10.1242/dev.153791. PubMed
Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions. Morita S, Horii T, Hatada I. Methods Mol Biol. 2018;1767:419-428. doi: 10.1007/978-1-4939-7774-1_23. PubMed
Up-regulation of NOX1/NADPH oxidase following drug-induced myocardial injury promotes cardiac dysfunction and fibrosis. Iwata K, Matsuno K, Murata A, Zhu K, Fukui H, Ikuta K, Katsuyama M, Ibi M, Matsumoto M, Ohigashi M, Wen X, Zhang J, Cui W, Yabe-Nishimura C. Free Radic Biol Med. 2018 May 20;120:277-288. doi: 10.1016/j.freeradbiomed.2018.03.053. Epub 2018 Mar 31. PubMed
Generation of Rat Monoclonal Antibodies Specific for DZIP3. Oikawa D, Shiota M, Tokunaga F, Wanibuchi H. Monoclon Antib Immunodiagn Immunother. 2018 Jun;37(3):153-157. doi: 10.1089/mab.2018.0005. Epub 2018 May 29. PubMed
Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis. Fiddes IT, Lodewijk GA, Mooring M, Bosworth CM, Ewing AD, Mantalas GL, Novak AM, van den Bout A, Bishara A, Rosenkrantz JL, Lorig-Roach R, Field AR, Haeussler M, Russo L, Bhaduri A, Nowakowski TJ, Pollen AA, Dougherty ML, Nuttle X, Addor MC, Zwolinski S, Katzman S, Kriegstein A, Eichler EE, Salama SR, Jacobs FMJ, Haussler D. Cell. 2018 May 31;173(6):1356-1369.e22. doi: 10.1016/j.cell.2018.03.051. Epub 2018 May 31. PubMed
NOX1/NADPH oxidase regulates the expression of multidrug resistance-associated protein 1 and maintains intracellular glutathione levels. Wen X, Iwata K, Ikuta K, Zhang X, Zhu K, Ibi M, Matsumoto M, Asaoka N, Liu J, Katsuyama M, Yabe-Nishimura C. FEBS J. 2019 Feb;286(4):678-687. doi: 10.1111/febs.14753. Epub 2019 Feb 6. PubMed
Involvement of ADAM12 in Chondrocyte Differentiation by Regulation of TGF-beta1-Induced IGF-1 and RUNX-2 Expressions. Horita M, Nishida K, Hasei J, Furumatsu T, Sakurai M, Onodera Y, Fukuda K, Salter DM, Ozaki T. Calcif Tissue Int. 2019 Jul;105(1):97-106. doi: 10.1007/s00223-019-00549-6. Epub 2019 Apr 16. PubMed
Anephrogenic phenotype induced by SALL1 gene knockout in pigs. Watanabe M, Nakano K, Uchikura A, Matsunari H, Yashima S, Umeyama K, Takayanagi S, Sakuma T, Yamamoto T, Morita S, Horii T, Hatada I, Nishinakamura R, Nakauchi H, Nagashima H. Sci Rep. 2019 May 29;9(1):8016. doi: 10.1038/s41598-019-44387-w. PubMed
Evolution of human brain-size associated NOTCH2NL genes proceeds towards reduced protein levels. Lodewijk GA, Fernandes DP, Vretzakis I, Savage JE, Jacobs FMJ. Mol Biol Evol. 2020 Apr 24. pii: 5824797. doi: 10.1093/molbev/msaa104. PubMed
Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-kappaB Activation Pathway. Oikawa D, Hatanaka N, Suzuki T, Tokunaga F. Front Immunol. 2020 Nov 23;11:601926. doi: 10.3389/fimmu.2020.601926. eCollection 2020. PubMed

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