pBABEpuro-HA-ERK2 GOF Citations (5)

Originally described in: Copper is required for oncogenic BRAF signalling and tumorigenesis.
Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM Nature. 2014 Apr 9. doi: 10.1038/nature13180. PubMed Journal

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Articles Citing pBABEpuro-HA-ERK2 GOF

Articles
Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs. Yue J, Lai F, Beckedorff F, Zhang A, Pastori C, Shiekhattar R. Genes Dev. 2017 Sep 1;31(17):1809-1820. doi: 10.1101/gad.301697.117. PubMed
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Li S, Song Y, Quach C, Guo H, Jang GB, Maazi H, Zhao S, Sands NA, Liu Q, In GK, Peng D, Yuan W, Machida K, Yu M, Akbari O, Hagiya A, Yang Y, Punj V, Tang L, Liang C. Nat Commun. 2019 Apr 12;10(1):1693. doi: 10.1038/s41467-019-09634-8. PubMed
Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma. Tsang T, Posimo JM, Gudiel AA, Cicchini M, Feldser DM, Brady DC. Nat Cell Biol. 2020 Apr;22(4):412-424. doi: 10.1038/s41556-020-0481-4. Epub 2020 Mar 16. PubMed
Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling. Tripathi R, Liu Z, Jain A, Lyon A, Meeks C, Richards D, Liu J, He D, Wang C, Nespi M, Rymar A, Wang P, Wilson M, Plattner R. Nat Commun. 2020 Oct 29;11(1):5463. doi: 10.1038/s41467-020-19075-3. PubMed
HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction. Clayton NS, Carter EP, Fearon AE, Heward JA, Rodriguez Fernandez L, Boughetane L, Wilkes EH, Cutillas PR, Grose RP. Int J Mol Sci. 2023 Mar 25;24(7):6228. doi: 10.3390/ijms24076228. PubMed

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