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HBV 1.3-mer X-null replicon Citations (3)

Originally described in: Genetic dissection of naturally occurring basal core promoter mutations of hepatitis B virus reveals a silent phenotype in the overlapping X gene.
Hussain Z, Jung HS, Ryu DK, Ryu WS J Gen Virol. 2009 Sep;90(Pt 9):2272-81. doi: 10.1099/vir.0.010421-0. Epub 2009 May 13.
PubMed Journal

Articles Citing HBV 1.3-mer X-null replicon

Hepatitis B virus X protein recruits methyltransferases to affect cotranscriptional N6-methyladenosine modification of viral/host RNAs. Kim GW, Siddiqui A. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3). pii: 2019455118. doi: 10.1073/pnas.2019455118. PubMed
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle. Lei Y, Xu X, Liu H, Chen L, Zhou H, Jiang J, Yang Y, Wu B. Autophagy. 2021 Dec;17(12):4423-4441. doi: 10.1080/15548627.2021.1917948. Epub 2021 Apr 27. PubMed
Identification of Estradiol Benzoate as an Inhibitor of HBx Using Inducible Stably Transfected HepG2 Cells Expressing HiBiT Tagged HBx. He J, Wu J, Chen J, Zhang S, Guo Y, Zhang X, Han J, Zhang Y, Guo Y, Lin Y, Yu W, Kong Y, Shen Z, Mao R, Zhang J. Molecules. 2022 Aug 6;27(15):5000. doi: 10.3390/molecules27155000. PubMed

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