MRGPRX2-Tango Citations (5)

Originally described in: PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.
Kroeze WK, Sassano MF, Huang XP, Lansu K, McCorvy JD, Giguere PM, Sciaky N, Roth BL Nat Struct Mol Biol. 2015 May;22(5):362-9. doi: 10.1038/nsmb.3014. Epub 2015 Apr 20. PubMed Journal

---

Articles Citing MRGPRX2-Tango

Articles
Species-specific pharmacology of maximakinin, an amphibian homologue of bradykinin: putative prodrug activity at the human B2 receptor and peptidase resistance in rats. Charest-Morin X, Bachelard H, Jean M, Marceau F. PeerJ. 2017 Jan 18;5:e2911. doi: 10.7717/peerj.2911. eCollection 2017. PubMed
Angiogenic Host Defense Peptide AG-30/5C and Bradykinin B2 Receptor Antagonist Icatibant Are G Protein Biased Agonists for MRGPRX2 in Mast Cells. Roy S, Ganguly A, Haque M, Ali H. J Immunol. 2019 Feb 15;202(4):1229-1238. doi: 10.4049/jimmunol.1801227. Epub 2019 Jan 16. PubMed
Substance P Serves as a Balanced Agonist for MRGPRX2 and a Single Tyrosine Residue Is Required for beta-Arrestin Recruitment and Receptor Internalization. Chompunud Na Ayudhya C, Amponnawarat A, Ali H. Int J Mol Sci. 2021 May 18;22(10). pii: ijms22105318. doi: 10.3390/ijms22105318. PubMed
Murepavadin, a Small Molecule Host Defense Peptide Mimetic, Activates Mast Cells via MRGPRX2 and MrgprB2. Amponnawarat A, Chompunud Na Ayudhya C, Ali H. Front Immunol. 2021 Jun 23;12:689410. doi: 10.3389/fimmu.2021.689410. eCollection 2021. PubMed
Lithocholic Acid Activates Mas-Related G Protein-Coupled Receptors, Contributing to Itch in Mice. Song MH, Shim WS. Biomol Ther (Seoul). 2021 Jul 15. pii: biomolther.2021.059. doi: 10.4062/biomolther.2021.059. PubMed

If you have published an article using this material, please email us at to have your article added to this page.