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pKLV2-U6gRNA5(BbsI)-PGKpuro2AmCherry-W Citations (7)

Originally described in: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJ, Iorio F, Pina C, Vassiliou GS, Yusa K Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079.
PubMed Journal

Articles Citing pKLV2-U6gRNA5(BbsI)-PGKpuro2AmCherry-W

Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells. Shi X, Kitano A, Jiang Y, Luu V, Hoegenauer KA, Nakada D. Exp Hematol. 2018 Aug;64:33-44.e5. doi: 10.1016/j.exphem.2018.04.009. Epub 2018 May 8. PubMed
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers. Schick S, Rendeiro AF, Runggatscher K, Ringler A, Boidol B, Hinkel M, Majek P, Vulliard L, Penz T, Parapatics K, Schmidl C, Menche J, Boehmelt G, Petronczki M, Muller AC, Bock C, Kubicek S. Nat Genet. 2019 Sep;51(9):1399-1410. doi: 10.1038/s41588-019-0477-9. Epub 2019 Aug 19. PubMed
Combinatorial CRISPR screen identifies fitness effects of gene paralogues. Thompson NA, Ranzani M, van der Weyden L, Iyer V, Offord V, Droop A, Behan F, Goncalves E, Speak A, Iorio F, Hewinson J, Harle V, Robertson H, Anderson E, Fu B, Yang F, Zagnoli-Vieira G, Chapman P, Del Castillo Velasco-Herrera M, Garnett MJ, Jackson SP, Adams DJ. Nat Commun. 2021 Feb 26;12(1):1302. doi: 10.1038/s41467-021-21478-9. PubMed
Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia. Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella JF, Thomas P, Sauvageau G, Adams DJ, Wong CC. Nat Commun. 2021 Apr 30;12(1):2482. doi: 10.1038/s41467-021-22750-8. PubMed
Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation. Ford K, Munson BP, Fong SH, Panwala R, Chu WK, Rainaldi J, Plongthongkum N, Arunachalam V, Kostrowicki J, Meluzzi D, Kreisberg JF, Jensen-Pergakes K, VanArsdale T, Paul T, Tamayo P, Zhang K, Bienkowska J, Mali P, Ideker T. Sci Rep. 2023 May 11;13(1):7678. doi: 10.1038/s41598-023-33329-2. PubMed
The interplay of DNA repair context with target sequence predictably biasses Cas9-generated mutations. Pallaseni A, Peets EM, Girling G, Crepaldi L, Kuzmin I, Raudvere U, Peterson H, Sercin O, Mardin BR, Kosicki M, Parts L. bioRxiv. 2023 Jun 28:2023.06.28.546891. doi: 10.1101/2023.06.28.546891. Preprint. PubMed
Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development. Bona N, Crossan GP. Nat Struct Mol Biol. 2023 Oct;30(10):1434-1445. doi: 10.1038/s41594-023-01067-8. Epub 2023 Aug 14. PubMed

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