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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.
Hata A, Lo RS, Wotton D, Lagna G, Massague J
Nature. 1997 Jul 3. 388(6637):82-7.
PubMed Article

Plasmids from Article

ID Plasmid  
14042CS2 Flag-Smad2
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14928CS2 Flag-Smad2 (100-467)
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14929CS2 Flag-Smad2 (1-185)
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14930pCMV5 Smad2-HA
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14958pCMV5 Flag-Smad2 (1-456)
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