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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.

Münger K, Phelps WC, Bubb V, Howley PM, Schlegel R
J Virol. 1989 Oct . 63(10):4417-21. (Link opens in a new window) PubMed

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