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DNA damage induces nuclear actin filament assembly by formin-2 and Spire-1/2 that promotes efficient DNA repair.
Belin BJ, Lee T, Mullins RD
Elife. 2015 Aug 19;4. doi: 10.7554/eLife.07735.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
58475pmCherry-C1 actin-3XNLS P2A mCherryExpresses nuclear-targeted human actin, with an mCherry expression reporter after a P2A protease cleavage site, on a CMV promoter
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58476pmCherry-C1 mCherry-NLSExpresses a nuclear-targeted mCherry control construct, on a CMV reporter
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58477pmCherry-C1 R62D actin-3XNLS P2A mCherryExpresses nuclear-targeted non-polymerizing R62D mutant of human actin, with an mCherry expression reporter after a P2A protease cleavage site, on a CMV promoter
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