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Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.
Theunissen TW, Costa Y, Radzisheuskaya A, van Oosten AL, Lavial F, Pain B, Castro LF, Silva JC
Development. 2011 Nov;138(22):4853-65. doi: 10.1242/dev.068775.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
74907pPB-CAG-cNanog-pgk-hphMammalian expression of cNanog
74909pPB-CAG-mNanogHD-pgk-hphMammalian expression of mNanog Homeodomain
74910pPB-CAG-zNanogHD-pgk-hphMammalian expression of zNanog Homeodomain
74911pPB-CAG-Flag3-pG-mNanog-pgk-hphMammalian expression of Flag tagged mNanog
74912pPB-CAG-Flag3-pG-cNanog-pgk-hphMammalian expression of Flag tagged cNanog
74913pPB-CAG-aBsx-pgk-hphMammalian expression of aBsx
74914pPB-CAG-mNanog-mut-pgk-hphMammalian expression of mNanog (Y42E, K43T)
74916pPB-CAG-aVent1-pgk-hphMammalian expresion of aVent1
74917pPB-CAG-rNanog-pgk-hphMammalian expression of rNanog

Antibodies from Article