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PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis.
Lee MS, Jeong MH, Lee HW, Han HJ, Ko A, Hewitt SM, Kim JH, Chun KH, Chung JY, Lee C, Cho H, Song J Nat Commun. 2015 Jul 17;6:7769. doi: 10.1038/ncomms8769.