Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures.
Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, Pillai MM
Oncogene. 2016 Aug 15. doi: 10.1038/onc.2016.279.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 82576 | pCDNA3.1-FLAG-SF3B1-WT | Expresses a codon-optimized ORF of human SF3B1 (wild-type) |
| 82577 | pCDNA3.1-FLAG-hSF3B1-K700E | Expresses a codon-optimized ORF of human SF3B1 ( K700E mutant) |