Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage.
Raikwar NS, Liu KZ, Thomas CP
Exp Cell Res. 2016 May 15;344(1):103-11. doi: 10.1016/j.yexcr.2016.03.020. Epub 2016 Mar 23. PubMed Article
Raikwar NS, Liu KZ, Thomas CP
Exp Cell Res. 2016 May 15;344(1):103-11. doi: 10.1016/j.yexcr.2016.03.020. Epub 2016 Mar 23. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 86034 | FLT1-KDR | chimera of human VEGFR1 extracellular domain with the TMD fused to the intracellular domain of VEGFR2 |
| 86035 | hFLT1 delta 754-763 | human VEGFR1 with a 10 amino acid deletion in EC close to TM domain |
| 86038 | hFlt1 V767A | human VEGFR1 with V to A mutation at position 767 |