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Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia.
Raikwar NS, Vandewalle A, Thomas CP
Am J Physiol Renal Physiol. 2010 Aug;299(2):F436-44. doi: 10.1152/ajprenal.00674.2009. Epub 2010 May 26. PubMed Article

Plasmids from Article

ID Plasmid Purpose
86041hNedd4-2 CSfull length NeddL3 with C to S mutation with His Xpress tag
86042Occludin_FlagFull length human occludin
86043OccludinMut_FlagFull length Occludin with mutation of PPPY domain at AA9-12 to PAAY

Antibodies from Article