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Noncanonical function of DGCR8 controls mESC exit from pluripotency.
Cirera-Salinas D, Yu J, Bodak M, Ngondo RP, Herbert KM, Ciaudo C
J Cell Biol. 2017 Jan 18. pii: jcb.201606073. doi: 10.1083/jcb.201606073. PubMed Article

Plasmids from Article

ID Plasmid Purpose
73525pX330-sgRNA_Dgcr8_1Expresses a human codon-optimized SpCas9 and sgRNA targeting Dgcr8
73526pX330-sgRNA_Dgcr8_2Expresses a human codon-optimized SpCas9 and sgRNA targeting Dgcr8
73527pX330-sgRNA_Dgcr8_3Expresses a human codon-optimized SpCas9 and sgRNA targeting Dgcr8
73528pX330-sgRNA_Dgcr8_4Expresses a human codon-optimized SpCas9 and sgRNA targeting Dgcr8
79860pX330-sgRNA_Drosha_1CRISPR/Cas9 DROSHA
79861pX330-sgRNA_Drosha_2CRISPR/Cas9 DROSHA
79862pX330-sgRNA_Drosha_3CRISPR/Cas9 DROSHA
79863pX330-sgRNA_Drosha_4CRISPR/Cas9 DROSHA

Antibodies from Article