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Locus-specific histone deacetylation using a synthetic CRISPR-Cas9-based HDAC.

Kwon DY, Zhao YT, Lamonica JM, Zhou Z
Nat Commun. 2017 May 12;8:15315. doi: 10.1038/ncomms15315. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
98591dCas9-hHDAC33rd generation lenti vector encoding dCas9-hHDAC3 (EF1a-NLS-dCas9(N863)-hHDAC3). Expresses dCas9 fused to human HDAC3.

Antibodies from Article