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Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
Showalter MR, Hatakeyama J, Cajka T, VanderVorst K, Carraway KL, Fiehn O
Elife. 2017 Jun 27;6. pii: e26030. doi: 10.7554/eLife.26030.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
87926pcDNA3.1-IDH2-WTExpresses IDH2 (wild-type) in mammalian cells
87927pcDNA3.1-IDH2-R172KExpresses IDH2 (R172K mutant) in mammalian cells

Antibodies from Article