Addgene: Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

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Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
Showalter MR, Hatakeyama J, Cajka T, VanderVorst K, Carraway KL, Fiehn O
Elife. 2017 Jun 27;6. pii: e26030. doi: 10.7554/eLife.26030. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
87926	pcDNA3.1-IDH2-WT	Expresses IDH2 (wild-type) in mammalian cells
87927	pcDNA3.1-IDH2-R172K	Expresses IDH2 (R172K mutant) in mammalian cells

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