Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.
Lei Y, Zhang X, Su J, Jeong M, Gundry MC, Huang YH, Zhou Y, Li W, Goodell MA
Nat Commun. 2017 Jul 11;8:16026. doi: 10.1038/ncomms16026.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
89633pcDNA3.1-dCas9-MQ1(WT)-EGFPTargeted CpG methylation
89635pcDNA3.1-dCas9-MQ1(C141S)-EGFPTargeted CpG methylation
89636pcDNA3.1-dCas9-MQ1(S317A)-EGFPTargeted CpG methylation
89637pcDNA3.1-dCas9-dMQ1-EGFPTargeted CpG methylation
89793pLV hUbC-dCas9-MQ1(Q147L)-EGFPTargeted CpG methylation
89794pLV hUbC-dCas9-dMQ1-EGFGTargeted CpG methylation

Antibodies from Article