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Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.
Lei Y, Zhang X, Su J, Jeong M, Gundry MC, Huang YH, Zhou Y, Li W, Goodell MA
Nat Commun. 2017 Jul 11;8:16026. doi: 10.1038/ncomms16026.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
89633pcDNA3.1-dCas9-MQ1(WT)-EGFPTargeted CpG methylation
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89634pcDNA3.1-dCas9-MQ1(Q147L)-EGFPTargeted CpG methylation
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89635pcDNA3.1-dCas9-MQ1(C141S)-EGFPTargeted CpG methylation
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89636pcDNA3.1-dCas9-MQ1(S317A)-EGFPTargeted CpG methylation
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89637pcDNA3.1-dCas9-dMQ1-EGFPTargeted CpG methylation
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89793pLV hUbC-dCas9-MQ1(Q147L)-EGFPTargeted CpG methylation
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89794pLV hUbC-dCas9-dMQ1-EGFGTargeted CpG methylation
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