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Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems.
Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sanchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V
Nat Neurosci. 2017 Aug;20(8):1172-1179. doi: 10.1038/nn.4593. Epub 2017 Jun 26.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
99113pAAV-TRE-mTurquoise2An AAV genome with tet-inducible expression of the fluorescent protein mTurquoise2
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99114pAAV-TRE-mRuby2An AAV genome with tet-inducible expression of the fluorescent protein mRuby2
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99115pAAV-TRE-DIO-mTurquoise2An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein mTurquoise2
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99117pAAV-TRE-DIO-mRuby2An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein mRuby2
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99118pAAV-CAG-tTAAn AAV genome that ubiquitously expresses tTA from the CAG promoter
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99119pAAV-hSyn1-tTAAn AAV genome that expresses tTA from the hSyn1 promoter
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99120pAAV-ihSyn1-tTAAn AAV genome that expresses tTA from the hSyn1 promoter that contains a positive feedback loop for amplifed expression of the tTA
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99121pAAV-ihSyn1-DIO-tTAAn AAV genome with Cre-dependent expression of the tTA from the hSyn1 promoter. Contains a positive feedback loop for amplifed expression of the tTA
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99122pAAV-CAG-mTurquoise2An AAV genome that ubiquitously expresses the fluorescent protein mTurquoise2 from the CAG promoter
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99123pAAV-CAG-mRuby2An AAV genome that ubiquitously expresses the fluorescent protein mRuby2 from the CAG promoter
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99125pAAV-hSyn1-mTurquoise2An AAV genome that expresses the fluorescent protein mTurquoise2 from the hSyn1 promoter
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99126pAAV-hSyn1-mRuby2An AAV genome that expresses the fluorescent protein mRuby2 from the hSyn1 promoter
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99128pAAV-mTH-GFPAn AAV genome that expresses GFP from the mouse TH promoter
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99129pAAV-GFAP-mKate2.5fAlso known as pAAV-GFAP-mKate2.5-f. An AAV genome that express the farnesylated fluorescent protein mKate2.5 from the GFAP promoter
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99130pAAV-mDlx-NLS-mRuby2An AAV genome that expresses nuclear localized mRuby2 from the mouse Dlx5/6 enhancer
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99131pAAV-TRE-mNeonGreenAn AAV genome with tet-inducible expression of the fluorescent protein mNeonGreen
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99132pAAV-TRE-DIO-mNeonGreenAn AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein mNeonGreen
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99133pAAV-CAG-fDIO-mNeonGreenAn AAV genome with Flp recombinase-dependent expression of mNeonGreen from the CAG promoter
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99134pAAV-CAG-mNeonGreenAn AAV genome that ubiquitously expresses the fluorescent protein mNeonGreen from the CAG promoter
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99135pAAV-hSyn1-mNeonGreenAn AAV genome that ubiquitously expresses the fluorescent protein mNeonGreen from the hSyn1 promoter
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103005pUCmini-iCAP-PHP.eBnon-standard AAV2 rep-AAV-PHP.eB cap plasmid with AAV cap expression controlled by a tTA-TRE amplifcation system
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103006pUCmini-iCAP-PHP.Snon-standard AAV2 rep-AAV-PHP.S cap plasmid with AAV cap expression controlled by a tTA-TRE amplifcation system
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