Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems.
Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sanchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V
Nat Neurosci. 2017 Aug;20(8):1172-1179. doi: 10.1038/nn.4593. Epub 2017 Jun 26. PubMed Article
Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sanchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V
Nat Neurosci. 2017 Aug;20(8):1172-1179. doi: 10.1038/nn.4593. Epub 2017 Jun 26. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 99113 | pAAV-TRE-mTurquoise2 | An AAV genome with tet-inducible expression of the fluorescent protein mTurquoise2 |
| 99114 | pAAV-TRE-mRuby2 | An AAV genome with tet-inducible expression of the fluorescent protein mRuby2 |
| 99115 | pAAV-TRE-DIO-mTurquoise2 | An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein mTurquoise2 |
| 99116 | pAAV-TRE-DIO-tdTomato | An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein tdTomato |
| 99117 | pAAV-TRE-DIO-mRuby2 | An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein mRuby2 |
| 99118 | pAAV-CAG-tTA | An AAV genome that ubiquitously expresses tTA from the CAG promoter |
| 99119 | pAAV-hSyn1-tTA | An AAV genome that expresses tTA from the hSyn1 promoter |
| 99120 | pAAV-ihSyn1-tTA | An AAV genome that expresses tTA from the hSyn1 promoter that contains a positive feedback loop for amplifed expression of the tTA |
| 99121 | pAAV-ihSyn1-DIO-tTA | An AAV genome with Cre-dependent expression of the tTA from the hSyn1 promoter. Contains a positive feedback loop for amplifed expression of the tTA |
| 99122 | pAAV-CAG-mTurquoise2 | An AAV genome that ubiquitously expresses the fluorescent protein mTurquoise2 from the CAG promoter |
| 99123 | pAAV-CAG-mRuby2 | An AAV genome that ubiquitously expresses the fluorescent protein mRuby2 from the CAG promoter |
| 99125 | pAAV-hSyn1-mTurquoise2 | An AAV genome that expresses the fluorescent protein mTurquoise2 from the hSyn1 promoter |
| 99126 | pAAV-hSyn1-mRuby2 | An AAV genome that expresses the fluorescent protein mRuby2 from the hSyn1 promoter |
| 99128 | pAAV-mTH-GFP | An AAV genome that expresses GFP from the mouse TH promoter |
| 99129 | pAAV-GFAP-mKate2.5f | Also known as pAAV-GFAP-mKate2.5-f. An AAV genome that express the farnesylated fluorescent protein mKate2.5 from the GFAP promoter |
| 99130 | pAAV-mDlx-NLS-mRuby2 | An AAV genome that expresses nuclear localized mRuby2 from the mouse Dlx5/6 enhancer |
| 99131 | pAAV-TRE-mNeonGreen | An AAV genome with tet-inducible expression of the fluorescent protein mNeonGreen |
| 99132 | pAAV-TRE-DIO-mNeonGreen | An AAV genome with tet-inducible, Cre-dependent expression of the fluorescent protein mNeonGreen |
| 99133 | pAAV-CAG-fDIO-mNeonGreen | An AAV genome with Flp recombinase-dependent expression of mNeonGreen from the CAG promoter |
| 99134 | pAAV-CAG-mNeonGreen | An AAV genome that ubiquitously expresses the fluorescent protein mNeonGreen from the CAG promoter |
| 99135 | pAAV-hSyn1-mNeonGreen | An AAV genome that ubiquitously expresses the fluorescent protein mNeonGreen from the hSyn1 promoter |
| 103005 | pUCmini-iCAP-PHP.eB | non-standard AAV2 rep-AAV-PHP.eB cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system |
| 103006 | pUCmini-iCAP-PHP.S | non-standard AAV2 rep-AAV-PHP.S cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system |