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Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.
Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR
Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug.
PubMed

Plasmids from Article

ID Plasmid Purpose  
100802BE4Expresses BE4 in mammalian cells
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100803AID-BE3Expresses AID-BE3 in mammalian cells
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100804CDA1-BE3Expresses CDA1-BE3 in mammalian cells
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100805SaBE4Expresses SaBE4 in mammalian cells
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100806BE4-GamExpresses BE4-Gam in mammalian cells
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100807BE3-GamExpresses BE3-Gam in mammalian cells
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100809SaBE4-GamExpresses SaBE4-Gam in mammalian cells
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100810SaBE3-GamExpresses SaBE3-Gam in mammalian cells
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