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Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.
Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR
Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug.

Plasmids from Article

ID Plasmid Purpose
100802BE4Expresses BE4 in mammalian cells
100803AID-BE3Expresses AID-BE3 in mammalian cells
100804CDA1-BE3Expresses CDA1-BE3 in mammalian cells
100805SaBE4Expresses SaBE4 in mammalian cells
100806BE4-GamExpresses BE4-Gam in mammalian cells
100807BE3-GamExpresses BE3-Gam in mammalian cells
100809SaBE4-GamExpresses SaBE4-Gam in mammalian cells
100810SaBE3-GamExpresses SaBE3-Gam in mammalian cells

Antibodies from Article