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Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior.
Bocchi R, Egervari K, Carol-Perdiguer L, Viale B, Quairiaux C, De Roo M, Boitard M, Oskouie S, Salmon P, Kiss JZ
Nat Commun. 2017 Oct 27;8(1):1158. doi: 10.1038/s41467-017-01046-w.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
114276pCWXPGR-pTF-DVL2deltaDIXTET-inducible expression of DVL2 protein with a deletion of its DIX-domain
114277pCWXPGR-pTF-dnTCF4TET-inducible expression of a dominant negative form of the TCF4 transcription factor
114283pCLXEBR-pTF-hM3DqTET-inducible expression of the hM3Dq protein
114287pCWXPGR-pTF-Wnt3aTET-inducible expression of Wnt3a
114293pCLXEBR-pTF-cKitTET-inducible expression of c-Kit
114294pCLX-MIFE-hM3Dq-PGK-mCherryMifepristone-inducible expression of hM3Dq protein
114322pCLX-G4E1b-R1DESTR2-MIFE-PGK-mCherryMifepristone-inducible lentiviral backbone for Gateway cloning of Gene insert together with constitutive mCherry expression

Antibodies from Article