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Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.
Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR
Nat Biotechnol. 2018 May 29. pii: nbt.4172. doi: 10.1038/nbt.4172.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
112093pCMV_BE4maxC:G-to-T:A base editing
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112094pCMV_AncBE4maxC:G-to-T:A base editing
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112095pCMV_ABEmaxA:T-to-G:C base editing
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112096pCMV_BE4max_3xHAC:G-to-T:A base editing
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112097pCMV_AncBE4max_3xHAC:G-to-T:A base editing
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112098pCMV_ABEmax_3xHAA:T-to-G:C base editing
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112099pCMV_BE4max_P2A_GFPC:G-to-T:A base editing
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112100pCMV_AncBE4max_P2A_GFPC:G-to-T:A base editing
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112101pCMV_ABEmax_P2A_GFPA:T-to-G:C base editing
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Antibodies from Article