Expanded CAG/CTG repeats resist gene silencing mediated by targeted Epigenome editing.
Yang B, Borgeaud AC, Buricova M, Aeschbach L, Rodriguez-Lima O, Ruiz Buendia GA, Cinesi C, Taylor AS, Baubec T, Dion V
Hum Mol Genet. 2021 Sep 7. pii: 6365982. doi: 10.1093/hmg/ddab255. PubMed Article
Yang B, Borgeaud AC, Buricova M, Aeschbach L, Rodriguez-Lima O, Ruiz Buendia GA, Cinesi C, Taylor AS, Baubec T, Dion V
Hum Mol Genet. 2021 Sep 7. pii: 6365982. doi: 10.1093/hmg/ddab255. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 114393 | pAB-NEO-PYL | For PYL expression |
| 114394 | pAB(EXPR-PYL-HDAC3-NEO) | For PYL-HDAC3 expression |
| 114395 | pAB(EXPR-PYL-HDAC5-NEO) | For PYL-HDAC5 expression |
| 114396 | pAB(EXPR-PYL-DNMT1-NEO) | For PYL-DNMT1 expression |
| 114397 | pAB-HDAC5(mut-H-A) | For PYL-HDAC5 H1006A expression |
| 114398 | pAB-HDAC5(mut-H-Y) | For PYL-HDAC5 H1006Y expression |
| 114399 | pAB(EXPR-DS-HDAC5_HDAC3) | For PYL-HDAC5 catalytic domain swap to HDAC3 catalytic domain expression |
| 114400 | pAB(EXPR-HDAC5-trun1) | For PYL-HDAC5 aa 1-275 expression |
| 114401 | pAB-EXPR(PYL-cat_dom_HDAC5) | For PYL-HDAC5 catalytic domain expression |
| 114402 | pAB-EXPR(PYL-Nterm_dom_HDAC5) | For PYL-HDAC5 N terminal domain expression |