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Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons.
Osaki T, Uzel SGM, Kamm RD
Sci Adv. 2018 Oct 10;4(10):eaat5847. doi: 10.1126/sciadv.aat5847. eCollection 2018 Oct.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
125255plenti2-EF1a-ChR2-EYFP-WRPE3rd gen lentiviral expression of ChR2 with mutation fused to EYFP driven by EF1a promoter for optogenetic activation
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125256pLEX307-EF1a-ChR2[H134R]-mCherry-Puro-WPRE3rd gen lentiviral expression of humanized ChR2 with H134R mutation fused to mCherry driven by EF1a promoter for optogenetic activation with puro selection
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Recombinant Antibodies from Article