Scalable, Continuous Evolution of Genes at Mutation Rates above Genomic Error Thresholds.
Ravikumar A, Arzumanyan GA, Obadi MKA, Javanpour AA, Liu CC
Cell. 2018 Dec 13;175(7):1946-1957.e13. doi: 10.1016/j.cell.2018.10.021. Epub 2018 Nov 8.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 130871 | pAR-Ec318 | A nuclear plasmid encoding the WT TP-DNAP1 for OrthoRep |
| 130872 | pAR-Ec611 | A nuclear plasmid encoding an error-prone mutant TP-DNAP1 (I777K, L900S) for OrthoRep |
| 130873 | pAR-Ec633 | A nuclear plasmid encoding an error-prone mutant TP-DNAP1 (L477V, L640Y, I777K, W814N) for OrthoRep |