Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility.
Tan Y, Kagan JC
Cell. 2019 Apr 4;177(2):384-398.e11. doi: 10.1016/j.cell.2019.01.039. Epub 2019 Mar 7. PubMed Article
Tan Y, Kagan JC
Cell. 2019 Apr 4;177(2):384-398.e11. doi: 10.1016/j.cell.2019.01.039. Epub 2019 Mar 7. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 131345 | pLentiCRISPRv2-TRAF6-targeting sgRNA 1 | gRNA targeting mouse TRAF6 |
| 131346 | pLentiCRISPRv2-TRAF6-targeting sgRNA 2 | gRNA targeting mouse TRAF6 |
| 131347 | pMSCV-IRES-GFP-MyD88-NpLxIS | Expresses MyD88 with 2 copies of pLxIS motif from STING fused to its N-ternimus |
| 131348 | pMSCV-IRES-GFP-MyD88-CpLxIS | Expresses MyD88 with 2 copies of pLxIS motif from STING fused to its C-terminus |
| 131349 | pMSCV-IRES-GFP-MyD88 (S34Y)-CpLxIS | Expresses MyD88 S34Y with 2 copies of pLxIS motif from STING fused to its C-terminus |
| 131350 | pMSCV-IRES-GFP-3xFLAG-MyD88-GyrB | Expresses MyD88 with an N-termial 3xFLAG tag and a C-terminal GyrB domain from the E. coli DNA Gyrase B |
| 131351 | pMSCV-IRES-GFP-3xFLAG-MyD88-V5 | Expresses MyD88 tagged with a 3xFLAG tag at its N-terminus and a V5 tag at its C-terminus |
| 131352 | pMSCV-IRES-GFP-MyD88-Rip3 | Expresses MyD88 with Rip3 fused to its C-terminus |
| 131353 | pMSCV-IRES-GFP-Caspase-1 (C285A) | Expresses Caspase-1 C285A |
| 131354 | pMSCV-IRES-GFP-Caspase-1 (C285A) -NpLxIS | Expresses Caspase-1 C285A with 2 copies of pLxIS motif from STING fused to its N-ternimus |
| 131355 | pMSCV-IRES-GFP-Caspase-1 (C285A) -CpLxIS | Expresses Caspase-1 C285A with 2 copies of pLxIS motif from STING fused to its C-ternimus |