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Programmable RNA-Guided RNA Effector Proteins Built from Human Parts.
Rauch S, He E, Srienc M, Zhou H, Zhang Z, Dickinson BC
Cell. 2019 Jun 27;178(1):122-134.e12. doi: 10.1016/j.cell.2019.05.049. Epub 2019 Jun 20. PubMed Article

Plasmids from Article

ID Plasmid Purpose
132543CIRTS-1: ORF5-TBP6.7-Pin domain-NLSExpresses CIRTS-1 (ORF5-TBP6.7-Pin domain-NLS) in mammalian cells
132544CIRTS-6: bdefensin 3-TBP6.7-YTHDF2(1-200)Expresses CIRTS-6 (bdefensin 3-TBP6.7-YTHDF2(1-200)) in mammalian cells
132545CIRTS-8: bdefensin 3-TBP6.7-hADAR(299-701)E488QExpresses CIRTS-8 (bdefensin 3-TBP6.7-hADAR(299-701)E488Q) in mammalian cells
132546CIRTS-10: bdefensin 3-SLBP-YTHDF2(1-200)Expresses CIRTS-10 (bdefensin 3-SLBP-YTHDF2(1-200)) in mammalian cells
132547TBP6.7 non-targeting gRNA lambda phageexpresses gRNA for TBP-based CIRTS
132548SLBP non-targeting gRNA lambda phageexpresses gRNA for SLBP-based CIRTS

Antibodies from Article