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A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene.
Kemaladewi DU, Bassi PS, Erwood S, Al-Basha D, Gawlik KI, Lindsay K, Hyatt E, Kember R, Place KM, Marks RM, Durbeej M, Prescott SA, Ivakine EA, Cohn RD
Nature. 2019 Aug;572(7767):125-130. doi: 10.1038/s41586-019-1430-x. Epub 2019 Jul 24.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
1353383XFLAG-VP64-SadCas9-NLS-VP643xFLAG VP64 SadCas9 for single guide cloning
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135339mLama1 AAV sgRNA 1, 2, 5Expression plasmid of VP64-SadCas9 sgRNA 1, 2 and 3
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