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Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis.
Fisch D, Bando H, Clough B, Hornung V, Yamamoto M, Shenoy AR, Frickel EM
EMBO J. 2019 Jul 1;38(13):e100926. doi: 10.15252/embj.2018100926. Epub 2019 Jun 3.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
138085pTet-CTRLpTet-CTRL encodes TetON and TetOFF transactivators. Can be transduced using Lentiviral particles
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138086pLenti-TetEmpty vector with Tet-response promoter for inducible expression of proteins. Can be transduced using Lentiviral particles
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138087pGene-TAP-GBP1Plasmid with TAP-GBP1 ORF
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138090pLenti-Tet-GBP1-C589ALentiviral backbone for inducible expression of human GBP1 missing the reactive cysteine of the CaaX-box (GBP1-C589A)
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Antibodies from Article