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Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors.
Doman JL, Raguram A, Newby GA, Liu DR
Nat Biotechnol. 2020 Feb 10. pii: 10.1038/s41587-020-0414-6. doi: 10.1038/s41587-020-0414-6.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
138155YE1-BE4maxC-to-T base editor
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138156YE2-BE4maxC-to-T base editor
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138157YEE-BE4maxC-to-T base editor
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138158EE-BE4maxC-to-T base editor
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138159YE1-BE4max-NGC-to-T base editor
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138160YE1-BE4max-CP1028C-to-T base editor
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138161AALN-BE4maxC-to-T base editor
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138162dead Sa Cas9For orthogonal R loop assay (use with Sp-derived base editor, Sp gRNA, and Sa gRNA for assay)
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