Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors.
Doman JL, Raguram A, Newby GA, Liu DR
Nat Biotechnol. 2020 Feb 10. pii: 10.1038/s41587-020-0414-6. doi: 10.1038/s41587-020-0414-6. PubMed Article
Doman JL, Raguram A, Newby GA, Liu DR
Nat Biotechnol. 2020 Feb 10. pii: 10.1038/s41587-020-0414-6. doi: 10.1038/s41587-020-0414-6. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 138155 | YE1-BE4max | C-to-T base editor |
| 138156 | YE2-BE4max | C-to-T base editor |
| 138157 | YEE-BE4max | C-to-T base editor |
| 138158 | EE-BE4max | C-to-T base editor |
| 138159 | YE1-BE4max-NG | C-to-T base editor |
| 138160 | YE1-BE4max-CP1028 | C-to-T base editor |
| 138161 | AALN-BE4max | C-to-T base editor |
| 138162 | dead Sa Cas9 | For orthogonal R loop assay (use with Sp-derived base editor, Sp gRNA, and Sa gRNA for assay) |