Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy.
Chang Y, Syahirah R, Wang X, Jin G, Torregrosa-Allen S, Elzey BD, Hummel SN, Wang T, Li C, Lian X, Deng Q, Broxmeyer HE, Bao X
Cell Rep. 2022 Jul 19;40(3):111128. doi: 10.1016/j.celrep.2022.111128. PubMed Article
Chang Y, Syahirah R, Wang X, Jin G, Torregrosa-Allen S, Elzey BD, Hummel SN, Wang T, Li C, Lian X, Deng Q, Broxmeyer HE, Bao X
Cell Rep. 2022 Jul 19;40(3):111128. doi: 10.1016/j.celrep.2022.111128. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 157742 | AAVS1-Puro CAG IL13-CAR | knock IL13-CAR into AAVS1 safe harbor locus for constitutive expression |
| 157743 | AAVS1-Puro CAG CLTX-CAR | knock CLTX-CAR into AAVS1 safe harbor locus for constitutive expression |
| 157744 | AAVS1-Puro CAG CLTX-NKG2D-2B4-CD3z CAR | knock CLTX-NKG2D-2B4-CD3z CAR into AAVS1 safe harbor locus for constitutive expression |