Multiplexed Functional Assessment of Genetic Variants in CARD11.
Meitlis I, Allenspach EJ, Bauman BM, Phan IQ, Dabbah G, Schmitt EG, Camp ND, Torgerson TR, Nickerson DA, Bamshad MJ, Hagin D, Luthers CR, Stinson JR, Gray J, Lundgren I, Church JA, Butte MJ, Jordan MB, Aceves SS, Schwartz DM, Milner JD, Schuval S, Skoda-Smith S, Cooper MA, Starita LM, Rawlings DJ, Snow AL, James RG
Am J Hum Genet. 2020 Nov 12. pii: S0002-9297(20)30373-6. doi: 10.1016/j.ajhg.2020.10.015. PubMed Article
Meitlis I, Allenspach EJ, Bauman BM, Phan IQ, Dabbah G, Schmitt EG, Camp ND, Torgerson TR, Nickerson DA, Bamshad MJ, Hagin D, Luthers CR, Stinson JR, Gray J, Lundgren I, Church JA, Butte MJ, Jordan MB, Aceves SS, Schwartz DM, Milner JD, Schuval S, Skoda-Smith S, Cooper MA, Starita LM, Rawlings DJ, Snow AL, James RG
Am J Hum Genet. 2020 Nov 12. pii: S0002-9297(20)30373-6. doi: 10.1016/j.ajhg.2020.10.015. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose | |
|---|---|---|---|
| 163770 | pRRL-MND-hCard11 delta e3-T2A-GFP | Expression of CARD domain variant with a deletion of exon 3 |
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| 163771 | pRRL-MND-hCard11 delta e4-T2A-GFP | Expression of CARD domain variant with a deletion of exon 4 |
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| 163772 | pRRL-MND-hCard11 delta e3-4-T2A-GFP | Expression of CARD domain variant with a deletion of exons 3 and 4. |
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| 163773 | pRRL-MND-hCard11 D58G-T2A-GFP | Expression of D58G CARD domain variant |
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| 163774 | pRRL-MND-hCard11 R35Q-T2A-GFP | Expression of R35Q CARD domain variant |
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| 163775 | pRRL-MND-hCard11 R35L-T2A-GFP | Expression of R35L CARD domain variant |
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| 163776 | pRRL-MND-hCard11 R35K-T2A-GFP | Expression of R35K CARD domain variant |
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| 163777 | pRRL-MND-hCard11 K41Q-T2A-GFP | Expression of K41Q CARD domain variant |
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| 163778 | pRRL-MND-hCard11 K41L-T2A-GFP | Expression of K41L CARD domain variant |
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| 163779 | pRRL-MND-hCard11 K41R-T2A-GFP | Expression of K41R CARD domain variant |
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| 163780 | pRRL-MND-hCard11 K69Q-T2A-GFP | Expression of K69Q CARD domain variant |
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| 163781 | pRRL-MND-hCard11 K69L-T2A-GFP | Expression of K69L CARD domain variant |
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| 163782 | pRRL-MND-hCard11 K69R-T2A-GFP | Expression of K69R CARD domain variant |
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| 163783 | pRRL-MND-hCard11 R72Q-T2A-GFP | Expression of R72Q CARD domain variant |
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| 163784 | pRRL-MND-hCard11 R72L-T2A-GFP | Expression of R72L CARD domain variant |
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| 163785 | pRRL-MND-hCard11 R72K-T2A-GFP | Expression of R72K CARD domain variant |
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| 163786 | pRRL-MND-hCard11 R30W-T2A-GFP | Expression of R30W CARD domain variant |
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| 163787 | pRRL-MND-hCard11 WT-T2A-GFP | Expression of Wild-type CARD11 |
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